Analysis of the therapeutic effect of caffeine citrate combined with poractant alfa injection in neonatal respiratory distress syndrome
Aim To analyze the therapeutic effect of caffeine citrate combined with poractant alfa injection in improving neo-natal respiratory distress syndrome(RDS).Methods 72 cases of neonatal RDS patients were randomly and equally divided into control group(treated with poractant alfa injection)and observation group(treated with caffeine citrate combined with poractant alfa in-jection).The therapeutic efficacy,blood gas index,respiratory mechanic index,treatment situation and adverse reactions between the two groups were compared.Results The total therapeutic rate of the observation group was higher than that of the control group(P＜0.05),and there was no significant difference in the incidence of adverse reactions between the two groups(P＞0.05).The observation group had lower oxygen therapy time,hospital stay,ventilation time,and clinical symptom relief time compared with the control group(P＜0.05).Compared with the parameters before treatment,after treatment,the partial pressure of oxygen and oxy-genation index of the two groups of children increased,while partial pressure of carbon dioxide was decreased,and the observation group was more significant than the control group(P＜0.05).Conclusion Caffeine citrate combined with poractant alfa injection has a significant therapeutic effect and good safety in neonatal RDS,and thus is worthy of clinical application.
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维普
