Research progress on mitochondria regulation of cell fate pathways
Mitochondria are dynamic and highly plastic organelles,and are the energy factories of cells,playing a role in regu-lating intracellular energy generation,metabolism,and signal transduction.Researches have shown that mitochondria regulate many biological processes,such as proliferation,apoptosis,aging,differentiation,and cell cycle,indicating that mitochondria play an im-portant biological role in regulating cell fate.This article reviews the mechanisms by which mitochondrial energy metabolism,mito-chondrial proteins,reactive oxygen species,mitochondrial DNA,and mitochondrial dynamics regulate cell fate,in order to provide new strategies and targets for the regulation of cell fate.
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