Investigation of the effects of amplitude integrated aEEG on the early diagnosis and prognosis prediction of infectious neonatal purulent meningitis
Aim To investigate the effects of amplitude integrated aEEG on the early diagnosis of infected neonatal purulent meningitis.Methods 52 newborns diagnosed with infection were collected,and divided into normal,mild abnormal and severe abnormal based on aEEG background activity within 24 h after diagnosis.Pele infant development scale at 6 months of birth and Ge-sell development scale at 12 months of birth were compared in each group.Cerebrospinal fluid biochemistry was used as the gold standard for evaluation,to determine the number of cases of purulent meningitis among 52 infected newborns.ROC was used to ana-lyze the diagnostic efficacy of aEEG on infected neonatal purulent meningitis.Results The infants were assessed as 31 normal,1 1 transition,and 10 abnormal at 6 months of birth based on Pele infant development scale,and the scores were significantly differ-ent among different groups with different aEEG levels(P＜0.05).The 3 parameters in Gesell development scores in children with abnormal aEEG were lower than those with normal aEEG(P＜0.05).Pyogenic meningitis was present in 10 children out of 52 in-fected neonates.The ROC curve analysis showed that the aEEG had good diagnostic efficacy for detecting neonatal suppurative meningitis.Conclusion The early diagnosis and prognosis prediction of infectious neonatal purulent meningitis by aEEG are of great significanc.
万方数据
维普
