Effects of modified Dachengqi decoction combined with Xuebijing on traditional Chinese medi-cine symptoms,inflammatory factors and clinical efficacy in patients with septic shock caused by peritonitis
Effects of modified Dachengqi decoction combined with Xuebijing on traditional Chinese medi-cine symptoms,inflammatory factors and clinical efficacy in patients with septic shock caused by peritonitis
Aim To explore the effects of Dachengqi decoction combined with Xuebijing on traditional Chinese medicine syndromes,inflammatory factors and clinical efficacy of septic shock patients caused by peritonitis.Methods The clinical data of 85 patients with septic shock caused by peritonitis in our hospital were retrospectively analyzed.According to different treatment methods,they were divided into Dachengqi decoction group(modified Dachengqi decoction treatment)with 27 cases,Xuebijing group(treated with Xuebijing treatment)with 22 cases,and combined group(modified Dachengqi decoction combined with Xuebijing treat-ment)with 36 cases.The traditional Chinese medicine syndrome score,inflammatory factor levels,stress indicators,coagulation function indicators levels,and clinical efficacy among different groups of patients were compared.Results After treatment,the traditional Chinese medicine syndrome score,inflammatory factor,and stress indicators levels in the three groups were significantly de-creased compared with them before treatment(P＜0.05),with lower levels in the combined group than the Dachengqi decoction group and the Xuebijing group(P＜0.05).The fibrinogen level significantly was increased compared with it before treatment(P＜0.05),and the combined group was higher than the Dachengqi decoction group and the Xuebijing group(P＜0.05).Activated partial throm-boplastin time and prothrombin time were significantly shortened compared with them before treatment(P＜0.05),and the combined group was shorter than the Dachengqi decoction group and the Xuebijing group(P＜0.05).The clinical efficacy of total effective rates of the combined group were higher than that of the Dachengqi decoction group and Xuebijing group(P＜0.05).Conclusion The combination of modified Dachengqi Decoction and Xuebijing can significantly reduce the traditional Chinese medicine syndrome score of septic shock patients caused by peritonitis,inhibit inflammatory reactions,alleviate stress reactions,and improve coagulation function.Its therapeutic effect is superior to that of modified Dachengqi decoction or Xuebijing treatment alone.
关键词
大承气汤/血必净/脓毒症休克/中医证候/炎症因子/临床疗效/腹膜炎
Key words
Dachengqi decoction/Xuebijing/septic shock/traditional Chinese medicine syndromes/inflammatory fac-tors/clinical efficacy/peritonitis
维普
万方数据