Observation of the therapeutic effects of acetylcysteine nebulization combined with azithromy-cin treatment on children with Mycoplasma pneumonia and airway mucus plug blockage
Aim To explore the effects of acetylcysteine nebulization combined with azithromycin treatment on children with Mycoplasma pneumonia and airway mucus plug blockage.Methods A total of 102 children with mycoplasma pneumonia with air-way mucus plug blockage were randomly divided into control group(azithromycin+bronchoalveolar lavage)and observation group(az-ithromycin+bronchoalveolar lavage+acetylcysteine).The levels of white blood cell count(WBC),C-reactive protein(CRP),and e-rythrocyte sedimentation rate(ESR)between two groups of children before and after treatment were compared.The imaging,bron-choscopy examination,and symptom improvement time after treatment in two groups were observed.Results The levels of WBC,CRP and ESR in the two groups were significantly decreased after treatment compared with those before treatment(P＜0.05),and they were lower in the observation group than those in the control group(P＜0.05).After treatment,the incidence of pleural effusion,bronchial mucosal erosion and granular hyperplasia in the observation group were lower than those in the control group(P＜0.05).The disappearance time of symptoms in the observation group were shorter than those in the control group(P＜0.05).Conclusion Acetylcysteine nebulization combined with azithromycin treatment can alleviate the inflammatory response in children with Mycoplasma pneumonia accompanied by airway mucus plug blockage,promote the disappearance of clinical symptoms,and facilitate early recovery of children's health.
万方数据
维普
