首页|基于列线图预测模型分析抑郁症患者发生院内感染的危险因素

基于列线图预测模型分析抑郁症患者发生院内感染的危险因素

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目的 应用列线图预测模型分析抑郁症患者发生院内感染的危险因素。方法 收集305例抑郁症住院患者的临床资料,多因素Logistic回归分析抑郁症患者发生院内感染的危险因素,建立列线图模型并进行预测模型的验证和效能评估。结果 抑郁症住院患者院内感染率为8。20%。感染组年龄>60岁、重度抑郁、合并糖尿病、使用抗抑郁药≥2种、侵入性操作、有营养不良风险患者占比均高于非感染组,住院时间长于非感染组,血红蛋白水平低于非感染组(P<0。05)。Logistic结果显示,年龄>60岁、住院时间>28天、使用抗抑郁药≥2种、侵入性操作、重度抑郁、营养不良风险是院内感染的独立危险因素(P<0。05)。建立的列线图预测模型预测院内感染的校正曲线趋近于理想曲线(P>0。05);模型预测的ROC下面积为0。850(P<0。05)。结论 年龄、住院时间、使用抗抑郁药种类数、侵入性操作、重度抑郁、营养不良风险均是抑郁症患者发生院内感染的独立危险因素,建立的列线图模型可直观评估院内感染的风险。
Risk factors for nosocomial infection in patients with depression based on nomogram predic-tion model
Aim To analyze the risk factors for nosocomial infection in patients with depression using a nomogram prediction model.Methods The clinical data of 305 depressive inpatients were collected.Multivariate Logistic regression analysis was used to identify risk factors for nosocomial infection in patients with depression.A nomogram model was established,and validation and performance evaluation of the predictive model were conducted.Results The nosocomial infection rate of inpatients with de-pression was 8.20%.The proportion of patients with age>60 years,severe depression,complicated with diabetes,number of using antidepressants ≥2,invasive procedures and at risk of malnutrition in the infection group was higher than that in the non-infection group,with longer hospital staying time as well as lower hemoglobin level(P<0.05)in infection group compared with non-infection group.Logistic analysis showed that age>60 years,hospital staying,number of use antidepressants≥2,invasive procedures,severe depression,and malnutrition risk were independent risk factors for nosocomial infection(P<0.05).The correction curve of nosoco-mial infection predicted by the nomogram model was close to the ideal curve(P>0.05).The area under ROC curve predicted by the model was 0.850(P<0.05).Conclusion Age,length of hospital staying,types of antidepressants,invasive procedures,severe depression,and risk of malnutrition are all independent risk factors for nosocomial infection in patients with depression.The estab-lished nomogram model can intuitively assess the risk of nosocomial infection.

depressionnosocomial infectionnomogramrisk factors

周晓飞、彭金燕、彭一鹏、罗会林

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武汉市红十字会医院神经外科,湖北武汉 430015

华中科技大学同济医学院附属协和医院神经外科,湖北武汉 430022

武汉市红十字会医院麻醉科,湖北武汉 430015

抑郁症 院内感染 列线图 危险因素

武汉市医学科研项目

WX21B26

2024

中南医学科学杂志
南华大学

中南医学科学杂志

CSTPCD
影响因子:0.757
ISSN:2095-1116
年,卷(期):2024.52(5)