With the accelerating pace of modern society,drinking occasions such as social activities have become increasingly integrated into daily life,making alcohol consumption a significant part of people's routines.Therefore,the development of efficient and safe sober-up products has emerged as a research hotspot.This experiment,grounded in safety and health,formulated a yogurt recipe using natural plants and new food ingredients.Through single-factor and orthogonal experiments,the optimal addition ratios and optimization of each ingredient were determined,leading to the development of a plant-based yogurt with alcohol detoxification and liver-protecting effects.Furthermore,the zebrafish model was employed to verify the yogurt's ability to improve post-intoxication behavior and enhance the activities of ADH and ALDH in vivo.The zebrafish sobriety validation experiments demonstrated that the plant-based yogurt developed in this study possesses notable alcohol detoxification properties.Consuming 31.2 μL/mL or more of this plant-based yogurt before drinking significantly alleviated the behavioral manifestations of intoxicated zebrafish,increased the activity of ADH enzymes in the body after drinking,accelerated alcohol metabolism,thereby mitigating post-drinking discomforts and protecting the liver.
关键词
葛根/姜黄/解酒保肝/斑马鱼实验
Key words
kudzu root/turmeric/alcohol detoxification and liver protection/zebrafish experiment
维普
万方数据