Research progress on mesenchymal stem cells in the treatment of liver cirrhosis
Liver cirrhosis is the end stage of chronic liver disease.Collagen is produced by activated hepatic stellate cells and accumulates in the extracellular matrix to form pseudolobules,leading to liver fibrosis and cirrhosis.Mesenchymal stem cells(MSCs)have the ability of multipotent differentiation and can be involved in cell therapy for a variety of diseases.In recent years,more and more experimental studies have proved that mesenchymal stem cells can participate in the treatment of liver cirrhosis.This article summarizes the research progress and prospect of mesenchymal stem cells in the treatment of liver cirrhosis.