Influencing factors of early cardiac systolic dysfunction in patients with craniocerebral trauma
Objective:To study the factors associated with early cardiac systolic dysfunction in patients with isolated traumatic brain injury(iTBI).Methods:The clinical data of 123 patients with simple craniocerebral trauma(iTBI)were collected and tested by echocardiography.According to the test results,the patients were divided into normal systolic function group(n=100)and incomplete systolic function group(n=23).The clinical data of patients in the 2 groups were com-pared,Logistic regression analysis was used to analyze the related factors influencing concurrent cardiac systolic dysfunction,and the receiver operating characteristics(ROC)curve was drawn to evaluate the predictive value of each index for concur-rent cardiac dysfunction in patients with iTBI.Results:Glasgow Coma(GCS)scores were lower in the normal systolic func-tion group;heart rate,systolic blood pressure and serum hs-cTnT were higher on admission than in the incomplete systolic function group(all P＜0.05).Multivariate Logistic regression analysis showed that heart rate,GCS score,and serum hs-cTnT at admission were the influencing factors of concurrent cardiac systolic dysfunction in patients with iTBI(all P＜0.05).The ROC curve analysis revealed that serum hs-cTnT level predicted the area,sensitivity,specificity and the Youden index in iTBI was higher than that of the heart rate and GCS score prediction at admission(all P＜0.05).Conclusion:Factors associated with early concurrent cardiac systolic insufficiency in iTBI include admission heart rate,GCS score,and serum hs-cTnT level,of which serum hs-cTnT level at admission had a higher efficacy to predict early complicated cardiac systolic insufficiency in iTBI patients.
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