New progress in treatment of pulmonary hypertension
Pulmonary hypertension(PH)is a clinical and pathophysiologic syndrome of elevated pulmonary vascular resistance and pulmonary arterial pressure due to structural or functional changes in the pulmonary vasculature caused by a variety of heterogenic diseases(etiology)and different pathogenic mechanisms,followed by the development of right heart failure or even death.PH is a major global health problem,and it can occur in people of all ages.In clinical practice,the treatment and management of PH is characterized by complexity,heterogeneity,and specialization,and requires an all-en-compassing,holistic,and multidisciplinary strategy of shared decision-making between doctors and patients.This article summarizes the advances in the treatment of PH in the light of the latest national and international guidelines and high-quality clinical studies and real-world data.