Effect of bronchoarterial embolization on hemoptysis of tuberculosis
Objective:To explore the effect of bronchial artery embolization(BAE)in the treatment of pulmonary tuber-culosis hemoptysis and its impact on prognosis.Methods:A retrospective study was conducted on the clinical data of 124 patients with pulmonary tuberculosis hemoptysis.According to different treatment methods,the patients were divided into an observation group(62 cases)and a control group(62 cases).The control group was treated with pituitary posterior lobe in-jection for hemostasis,and the observation group was treated with BAE in addition to basic treatment.The changes of levels of serum basic fibroblast growth factor(bFGF)and vascular endothelial growth factor-A(VEGF-A),interleukin-1(IL-1),IL-6,IL-10 and immunoglobulin IgG,IgA,IgM were compared between the two groups before and after treatment.The adverse reactions were observed,and the clinical efficacy and prognosis were compared.Results:The total effective rate in the observation group was 95.16％,which was significantly higher than 82.26％of the control group(P＜0.05).Compared with before treatment,the levels of serum bFGF,VEGF-A,IL-1 and IL-6 decreased,IL-10,IgG,IgA and IgM increased in the two groups after treatment(all P＜0.05).Compared with the control group,the levels of serum bFGF,VEGF-A,IL-1 and IL-6 decreased,IL-10,IgG,IgA and IgM increased in the observation group after treatment(all P＜0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P＞0.05).The total mortality of hemoptysis in the observation group was significantly lower than that in the control group(P＜0.05).Conclusions:BAE is effective in the treatment of pulmonary tuberculosis hemoptysis,and can reduce the level of inflammato-ry factors,and improve the immune function and prognosis.
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