Evaluation value of neutrophil-to-albumin ratio combined with A-DROP score in prognosis of severe community-acquired pneumonia
Objective:To investigate the prognostic value of neutrophil to albumin ratio(NAR)combined with A-DROP score in patients with severe community-acquired pneumonia(SCAP).Methods:The clinical data of 73 SCAP patients were collected,and the SCAP patients were divided into the survival group(40 patients)and the death group(33 patients)according to their survival status within 30 days of hospitalization.The clinical indexes of patients in the 2 groups were compared,Spearman's method was used to analyze the correlation between NAR and A-DROP scores in SCAP patients,multifactorial logistic regression model was used to predict the factors affecting the prognosis of SCAP,and ROC curves were applied to analyze the value of NAR combined with A-DROP scores in assessing the prognosis of SCAP patients.Results:NAR and A-DROP scores in the death group were significantly higher than those in the survival group,and albumin levels,lymphocyte counts,oxygenation index,and partial pressure of arterial oxygen(PaO2)were significantly lower than those in the survival group(all P<0.05).NAR and A-DROP scores were positively correlated in SCAP patients(r=0.425,P<0.05),and NAR and A-DROP scores could serve as independent risk factors for the prognosis of SCAP patients at 30 days of admission(all P<0.05).The AUCs of NAR and A-DROP scores alone and in combination for predicting 30 days admis-sion prognosis in SCAP patients were 0.813(95%CI:0.715-0.911),0.836(95%CI:0.736-0.935),and 0.908(95%CI:0.834-0.981),respectively.Conclusion:NAR and A-DROP score can be used as independent risk factors for predic-ting the 30-day prognosis of SCAP patients,and the combination of NAR and A-DROP score can improve the predictive value.
Severe community-acquired pneumoniaNeutrophil to albumin ratioA-DROP scorePrognosis