首页|免疫检查点抑制剂相关肺炎的诊治进展

免疫检查点抑制剂相关肺炎的诊治进展

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随着现代医学的飞速发展,免疫治疗成为继放疗、化疗等传统治疗方式之后,一种新兴的肿瘤治疗手段,为多种肿瘤的治疗开辟了新的途径.然而,随着免疫治疗的广泛应用,免疫检查点抑制剂相关的不良事件逐渐增多,免疫检查点抑制剂相关肺炎便是其中一种发病率低、具有潜在致死性、缺乏特异性临床表现、临床诊断困难的不良事件.本文拟综述免疫检查点抑制剂相关肺炎的流行病学、发病机制、危险因素、临床表现、诊断及治疗的研究进展,为临床早期诊断和治疗提供参考.
Advances in the diagnosis and treatment of immune checkpoint inhibitor-related pneumonitis
With the rapid advancements of modern medicine,immunotherapy is now being used to treat a variety of tumors,providing a new treatment option beyond conventional treatments like chemotherapy and radiation.Nonetheless,with the widespread use of immunotherapy,there has been a gradual increase in immune checkpoint inhibitor-related adverse events.One such adverse event is immune checkpoint inhibitor-related pneumonitis(CIP).It has low incidence,potential lethality,a lack of specific clinical manifestations,and difficulties in clinical diagnosis.In this article,we hope to offer a useful resource for the prompt diagnosis and efficient treatment of CIP by providing a thorough review of the latest research findings on the epidemiology,pathophysiology,risk factors,clinical manifestations,diagnosis,and treatment of CIP.

Immune checkpoint inhibitor-related pneumonitisImmune checkpoint inhibitorsTumorImmune-related adverse events

张格、向菲

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华中科技大学同济医学院附属协和医院呼吸与危重症医学科,湖北武汉 430022

免疫检查点抑制剂相关肺炎 免疫检查点抑制剂 肿瘤 免疫相关不良事件

2024

内科急危重症杂志
华中科技大学同济医学院

内科急危重症杂志

CSTPCD
影响因子:0.947
ISSN:1007-1024
年,卷(期):2024.30(5)