Research progress in the treatment of extramedullary disease
Extramedullary disease(EMD)is a kind of plasmacytoma,which is a soft tissue tumor formed by plasmacy-toma penetrating the bone cortex or outside the bone.It has the characteristics of high invasion and poor prognosis.At pres-ent,the pathogenesis of EMD is not clear,and there is no unified standard for treatment.Proteasome inhibitors combined with immunomodulators,monoclonal antibodies,autologous hematologist stem cell transplantion,chimeric antigen receptor T-cell(CAR-T),and targeted drugs can be selected for treatment.This article will summarize the latest research progress on EMD treatment to provide a reference for clinical work.