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中医护理预防髋关节置换术后下肢深静脉血栓的Meta分析

Traditional Chinese Medicine Nursing Prevention of Lower Extremity Deep Vein Thrombosis After hip Replacement:A Meta-analysis

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目的 系统评价髋关节置换术后中医护理预防下肢深静脉血栓形成的临床效果.方法 计算机检索PubMed、国家知识基础设施数据库(CNKI)、维普资讯中文期刊服务平台(VIP)、万方学术期刊全文数据库(Wanfang)中关于髋关节置换术后中医护理预防下肢深静脉血栓形成的文献,检索时间为2012-2022年11月.采用Cochrane干预措施系统评价手册(5.1.0版)偏倚风险评估工具对纳入的随机对照研究进行质量评价,运用RevMan5.4软件对纳入文献进行Meta分析.结果 纳入11项研究,涉及1087例患者,其中研究组597例,对照组508例.Meta分析结果显示:中医护理下肢深静脉血栓发生率低于常规护理[RR=0.18,95%CI(0.09~0.35),Z=5.03,P<0.00001].中医护理髋关节置换术后患者纤维蛋白原降低程度较常规护理明显[MD=-0.47,95%CI(-0.77~-0.16),Z=2.96,P=0.003],差异有统计学意义(P<0.05).中医护理凝血酶原时间[MD=1.86,95%CI(-1.64~5.36),Z=1.04,P=0.30]、活化部分凝血活酶时间[MD=3.77,95%CI(-1.84~9.38),Z=1.32,P=0.19]与常规护理比较差异无统计学意义(P>0.05).结论 研究结果表明,髋关节置换术后,中医护理对预防下肢深静脉血栓形成有一定效果,且能显著降低纤维蛋白原,但在改善凝血酶原时间和活化部分凝血活酶时间方面,其效果与常规护理相比差异无统计学意义,受纳入范围和纳入研究质量的影响,上述结论尚待更多高质量的试验予以证实.
Objective To systematically evaluate the clinical effect of traditional Chinese medicine nursing on reducing the incidence of deep vein thrombosis of lower limbs after hip replacement.Methods The computer searched PubMed,China National Knowledge Infrastructure(CNKI),VIP and Wanfang Data Knowledge Ser-vice Platform for the literature on the prevention of lower limb deep vein thrombosis by TCM nursing after hip replacement.The retrieval time was from 2012 to November 2022.Cochrane System Evaluation Manual 5.1 Bias Risk Assessment Tool was used to evaluate the quality of the included randomized controlled studies,and RevMan5.4 software was used to conduct Meta-analysis of the included literature.Results Eleven studies were included,involving 1087 patients,including 579 in the study group and 508 in the control group.Meta analysis results show that:The incidence of lower limb deep vein thrombosis in the TCM nursing group was low-er than that in the conventional nursing group[RR=0.18,95%CI(0.09-0.35),Z=5.03,P<0.00001].The fibrinogen level of patients after hip replacement was significantly lower in the TCM nursing group than that in the conventional nursing group[MD=-0.47,95%CI(-0.77--0.16),Z=2.96,P=0.003].The differ-ence was statistically significant.There was no significant difference between prothrombin time[MD=1.86,95%CI(-1.64-5.36),Z=1.04,P=0.30],Patial thromboplastin time[MD=3.77,95%CI(-1.84-9.38),Z=1.32,P=0.19]and routine nursing care.Conclusion The research results show that after hip re-placement,traditional Chinese medicine nursing has a certain effect in preventing lower limb deep vein thrombo-sis,and can significantly reduce fibrinogen,but its effect in improving prothrombin time and activated site thromboplastin time is no different from conventional nursing.Affected by the scope of inclusion and the quality of inclusion,the above conclusions need to be confirmed by more high-quality experiments.

TCM nursingHip replacementLower extremity deep vein thrombosisMeta analysisCoag-ulation function

张洪丽、顾晨丛、杨晓敏、魏丽丽、杨毅捷、胡春娜、韩刚、杨桐、王利春

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河北省沧州中西医结合医院骨科康复院区,河北沧州 061000

河北中医学院,石家庄 050091

承德医学院,河北承德 067000

中医护理 髋关节置换术 下肢深静脉血栓 Meta分析 凝血功能

2024

内蒙古医学杂志
内蒙古自治区医学会

内蒙古医学杂志

影响因子:0.537
ISSN:1004-0951
年,卷(期):2024.56(4)