Objective To explore changes in left ventricular systolic function in severe tricuspid regurgita-tion(TR)using noninvasive myocardial work technology via echocardiography and evaluate the effectiveness of this technology in assessing left ventricular systolic function in patients with severe TR.Methods Thirty pa-tients with severe TR were selected as the case group,and 18 individuals with mild TR(physiological),matched for age and gender,with tricuspid regurgitation jet width(VCW)≤3 mm and pulmonary artery sys-tolic pressure(PASP)≤30 mm Hg were chosen as the control group.Images and conventional left ventricular systolic function parameters,along with myocardial work parameters,were collected and analyzed using the GE Vivid E95 color Doppler ultrasound diagnostic system and GE Echo PAC ultrasound analysis workstation.Results In the case group,PASP,left atrial anteroposterior diameter,and VCW were significantly higher than those in the control group(P＜0.01).The left ventricular ejection fraction(LVEF)in the case group was lower com-pared to the control group(P＜0.01).The absolute value of global longitudinal strain(GLS),global work index(GWI),global constructive work(GCW),and global work efficiency(GWE)were significantly decreased(P＜0.01),while global wasted work(GWW)was significantly higher in the case group(P＜0.01).Left ven-tricular GWE,GWI,GCW were negatively correlated with VCW(P＜0.05),and GWW was positively correlat-ed with VCW(P＜0.05);left ventricular GWE,GWI,GCW were negatively correlated with GLS(P＜0.01),and GWW was positively correlated with GLS(P＜0.05).Conclusion Noninvasive myocardial work technolo-gy can accurately assess changes in left ventricular myocardial work parameters and systolic function in patients with severe TR,confirming early significant changes in left ventricular systolic function in these patients.
left ventricular systolic functionnoninvasive myocardial work technologytricuspid regurgitation
维普
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