Objective To investigate the relationship between high-sensitivity C-reactive protein level and TIMI blood flow grading and Gensini score in STEMI patients.Methods A total of 288 STEMI patients who underwent emergency PCI in Bayannur City Hospital from January 2021 to December 2021 were collected,and the study subjects were divided into Group A(TIMI grade 0-1 186 cases)and Group B(TIMI grade 2-3102 cases),mild(Gensini score≤81 145 cases)and severe(Gensini score＞81 points 143 cases),respectively,compared the clinical data of patients in the two groups and analyze the correlation between hs-CRP levels and pre-PCI coronary flow grade reduction and degree of coronary artery disease in STEMI patients.Results The hs-CRP levels of patients with TIMI grades 2-3 were significantly lower than those of patients with TIMI grades 0-1(P=0.01),and the results of the Spearman correlation coefficient method showed a significant negative correlation between serum hs-CRP and preoperative TIMI blood flow(r=-0.174,P＜0.01),and the results of the multifactorial regression analysis indicated that hs-CRP was a TIMI blood flow risk factor for decreased TIMI blood flow(OR=0.819,95％CI:0.683-0.982,P＜0.05),suggesting that hs-CRP was a predictor of decreased preoperative TIMI blood flow.In addition,the level of serum hs-CRP in patients in the mild group was smaller than that in patients in the severe group(P＜0.05),and the results of Spearman's cor-relation coefficient method analysis showed a positive correlation between hs-CRP and Gensini scores of patients with STEMI(r=0.140,P=0.017),which indicated that the higher the level of hs-CRP in the patients,the higher the Gensini scores were.Conclusion In this study,we found a significant correlation between hs-CRP levels and preoperative TIMI blood flow reduction and Gensini score in STEMI patients.
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