首页|急性缺血性卒中血管内治疗临床预后相关危险因素研究

急性缺血性卒中血管内治疗临床预后相关危险因素研究

Study on Prognostic Factors related to Endovascular Therapy in Acute Ischemic Stroke

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目的 回顾性分析急性缺血性卒中血管内治疗影响预后的相关危险因素.方法 选取2018年6月至2022年12月确诊为急性前循环大血管闭塞所致的急性缺血性卒中患者70例.所有患者在24h内行血管内治疗(endovascular thrombectomy,EVT),应用改良Rankin评分(mRS)评估两组患者EVT术后90 d神经功能恢复情况.根据mRS评分将患者分为预后良好组(mRS≤2分)和预后不良组(mRS≥3分).比较两组间差异,将两组间数据进行二元Logistic回归分析得出风险相关性,制成受试者工作特征曲线(ROC),用于指导及评价EVT后患者预后的转归.结果 两组患者基线血糖、基线NIHSS评分、发病至穿刺时间(OTP)、穿刺至再通时间(PTR)、术后症状性颅内出血(sICH)转化比较差异具有统计学意义(P<0.05).二元 Logistic 回归分析结果显示:血糖水平(OR=1.657,95%CI 1.101~2.495,P<0.05)、OTP(OR=1.008,95%CI 1.000~1.016,P<0.05)、PTR(OR=1.054,95%CI 1.010~1.099,P<0.05)、sICH(OR=142.469,95%CI 7.161~2834.522,P<0.05)是预后不良的独立危险因素.结论 术前血糖升高、OTP及PTR延长、术后sICH是影响AIS患者EVT预后的独立危险因素.
Objective:To analyze retrospectively the risk factors of endovascular therapy affecting prognosis of a-cute ischemic stroke.Methods A total of 70 patients with acute ischemic stroke diagnosed with acute anterior circulation large vessel occlusion from June 2018 to December 2022 were selected.All patients received Endovascular thrombectomy(EVT)within 24h,and improved Rankin score(mRS)was used to evaluate the recovery of nerve function at 90 days after EVT.According to mRS Scores,the patients were divided into good prognosis group(mRS≤2 points)and poor prognosis group(mRS≥3 points).The difference between the two groups was compared,and the data between the two groups were analyzed by binary Logistic regression to obtain the risk correlation,and the working curve(ROC)was made to guide and evaluate the prognosis of patients after EVT.Results There were significant differences in baseline blood glucose,baseline NIHSS score,OTP,PTR and postoperative sICH transformation between the two groups(P<0.05).Bi-nary Logistic regression analysis results showed:Blood glucose level(OR=1.657,95%CI 1.101-2.495,P<0.05),time from onset to puncture(OR=1.008,95%CI 1.000-1.016,P<0.05),time from puncture to recalculation(OR=1.054,95%CI 1.010-1.099,P<0.05)and symptomatic intracranial hemorrhage(OR=142.469,95%CI 7.161-2834.522,P<0.05)were independent risk factors for poor prognosis.Conclusions Preoperative elevated blood glucose,prolonged OTP and PTR,and postoperative sICH were independent risk factors for EVT prognosis in AIS patients.

acute ischemic strokeendovascular therapyrecanalizationmRS

李明月、袁军

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达拉特旗人民医院,内蒙古鄂尔多斯 014300

内蒙古自治区人民医院神经内科,呼和浩特 010017

急性缺血性卒中 血管内治疗 血管再通 改良Rankin评分

2022年度内蒙古自治区卫生健康科技计划项目

202201043

2024

内蒙古医学杂志
内蒙古自治区医学会

内蒙古医学杂志

影响因子:0.537
ISSN:1004-0951
年,卷(期):2024.56(8)
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