首页|PCNL术后发生SIRS的危险因素分析

PCNL术后发生SIRS的危险因素分析

扫码查看
目的:探讨经皮肾镜取石术(percutaneous nephrolithotomy,PCNL)术后发生全身炎症反应综合征(systemic inflammatory response syndrome,SIRS)的危险因素,为制订防治SIRS发生的方案提供参考.方法:回顾性分析 2019 年 1月—2020 年 12 月于南通大学附属常熟医院行PCNL 97 例患者的临床资料.根据术后是否出现SIRS,分为SIRS组和非SIRS组.比较两组患者性别、年龄、BMI、高血压病、糖尿病、术前尿WBC、肾周脂肪条索影(perirenal fat stranding,PFS)、结石长径、手术通道、手术时间的差异.使用多因素Logistic回归分析SIRS发生的危险因素.结果:两组患者性别、年龄、BMI、高血压病、糖尿病、结石长径、手术通道、手术时间差异均无统计学意义(均P>0.05);术前尿WBC、PFS差异有统计学意义(P<0.05).纳入BMI、糖尿病、术前尿WBC、PFS、手术通道和手术时间行多因素Logistic 回归分析显示,术前尿WBC阳性、存在PFS是SIRS发生的独立危险因素(P<0.05).结论:PCNL术后发生SIRS和术前尿WBC阳性、存在PFS相关,关注术前尿WBC和PFS,必要时给予充分的抗感染治疗可能是减少SIRS发生的重要措施.
Analysis of risk factors for post-PCNL SIRS
Objective:The study investigates the risk factors for the occurrence of systemic inflammatory response syndrome(SIRS)after percutaneous nephrolithotomy(PCNL),aiming to provide reference for the development of strategies to prevent and treat SIRS.Methods:A retrospective analysis was conducted on the clinical data of 97 patients who underwent PCNL at the Affiliated Changshu Hospital of Nantong University from January 2019 to December 2020.The patients were divided into SIRS group and non-SIRS group based on the presence or absence of SIRS after surgery.The differences in gender,age,BMI,hypertension,diabetes,preoperative WBC count,perirenal fat stranding(PFS),stone size,surgical approach,and operative time were compared between the two groups.Multivariate Logistic regression analysis was employed to identify the risk factors for the occurrence of SIRS.Results:The two groups showed no statistically significant differences in terms of gender,age,BMI,hypertension,diabetes,stone size,surgical approach,and operative time(all P>0.05).However,there were statistically significant differences in preoperative WBC count and PFS between the two groups(P<0.05).Multivariate Logistic regression analysis,incorporating BMI,diabetes,preoperative WBC count,PFS,surgical approach,and operative time,revealed that a positive preoperative WBC count and the presence of PFS were independent risk factors for the occurrence of SIRS(P<0.05).Conclusion:The occurrence of SIRS after PCNL is correlated with preoperative positive WBC count and the presence of PFS.Focusing on preoperative WBC count and PFS,providing adequate antimicrobial treatment when necessary may be an impor-tant measure to reduce the occurrence of SIRS.

systemic inflammatory response syndromepercutaneous nephrolithotomyperirenal fat strandingrisk factors

付振宇、陆珂、胡俊、石鸣、于慕渊、贝明龙、顾怡峰、陈永昌、张鸽

展开 >

南通大学附属常熟医院泌尿外科,江苏 215500

全身炎症反应综合征 经皮肾镜取石术 肾周脂肪条索影 危险因素

南通大学附属常熟医院面上项目

CSEY2021047

2024

南通大学学报(医学版)
南通大学

南通大学学报(医学版)

影响因子:0.637
ISSN:1674-7887
年,卷(期):2024.44(2)