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血管内治疗症状性非急性颅内动脉闭塞失败的危险因素分析

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目的 探讨血管内治疗症状性非急性颅内动脉闭塞(IAO)失败的危险因素.方法 选取2021年1月至2024年4月徐州医科大学附属宿迁医院行血管内治疗的157例症状性非急性IAO患者为研究对象,根据手术方式分为机械取栓组、球囊扩张组和支架置入组;根据术后血管再通情况分为成功组和失败组.对比不同组别患者临床一般资料、影像学指标及实验室指标水平,分析IAO血管内治疗效果的影响因素.结果 157例接受血管内治疗后闭塞血管成功再通128例,成功率为81.53%.与成功组相比,失败组患者预估血管闭塞时间更长、Alberta卒中项目早期CT评分(ASPECTS)评分低、闭塞血管长度更长、无残端/圆钝形残端及侧支循环分级0~2级比例更高(P<0.05).Logistic回归分析显示,估算闭塞时间、ASPECTS评分、闭塞血管长度、闭塞残端及侧支循环分级是影响血管内治疗效果的独立因素(P<0.05).结论 症状性非急性IAO患者血管内治疗再通率相对较高,但ASPECTS评分、血管闭塞时间和闭塞血管长度、血栓残端形态及侧支循环状况均会影响血管内治疗效果.
Analysis of risk factors for failure of symptomatic non-acute intracranial artery occlusion by endovascular therapy
Objective To investigate the risk factors of failure of endovascular treatment for symptomatic non-acute intracranial artery occlusion(IAO).Methods A total of 157 patients with symptomatic non-acute IAO who underwent endovascular treatment in Suqian Hospital Affiliated to Xuzhou Medical University from January 2021 to April 2024 were selected as the study objects.According to the surgical method,the patients were divided into thrombectomy group,balloon dilatation group and stent implantation group,then they were divided into successful group and failed group according to postoperative vascular recanalization.The clinical basic data,imaging indexes and laboratory indexes of the two groups were compared.The factors influencing the effect of endovascular therapy in patients with symptomatic non-acute intracranial artery occlusion were analyzed.Results In 157 cases,128 cases were successfully recanalized after vascular therapy,the success rate was 81.53%.Compared with the successful group,patients in the failure group had longer estimated vascular occlusion time,lower ASPECTS score,longer occlusive vessel length,higher proportion of no stump/round blunt stump and collateral circulation grade 0-2(P<0.05).Logistic regression analysis showed that estimated occlusion time,ASPECTS score,occlusive vessel length,occlusive stump and collateral circulation grade were independent factors affecting the effect of intravascular therapy(P<0.05).Conclusion Endovascular revascularization rate is higher in symptomatic non-acute IAO patients,but ASPECTS score,occlusion time and length,stump shape and collateral circulation can affect the effect of endovascular therapy.

SymptomaticNon-acuteIntracranial artery occlusionEndovascular therapyInfluencing factor

张雪玲、王一峰、王黎明、赵芃、孙威

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223800 江苏,徐州医科大学附属宿迁医院神经内科

症状性 非急性 颅内动脉闭塞 血管内治疗 影响因素

2025

脑与神经疾病杂志
华北地区三省二市神经病学学会协作组,河北医科大学第二医院

脑与神经疾病杂志

影响因子:0.865
ISSN:1006-351X
年,卷(期):2025.33(1)