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卒中后眩晕患者认知功能障碍风险预警模型构建

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目的 探讨脑卒中后眩晕患者认知功能障碍影响因素,并构建风险预警模型.方法 分析2021年4月至2024年5月南京医科大学附属脑科医院中医科及神经内科收治的205例脑卒中后眩晕患者一般临床资料,根据患者是否出现认知功能障碍分为认知功能障碍组(n=79)、认知功能正常组(n=126),对比两组一般临床资料,分析影响脑卒中后眩晕患者认知功能的危险因素,以危险因素构建风险预警模型,以受试者工作特征(ROC)曲线探究模型在脑卒中后眩晕患者认知功能中的预测效能.结果 两组患者居住地、受教育年限、饮酒、眩晕程度、卒中次数、病灶部位、脑白质疏松比较差异有统计学意义(P<0.05);Logistic回归分析发现,饮酒、高血压、重度眩晕、病灶部位在额叶、脑白质疏松是影响脑卒中后眩晕患者认知功能障碍的独立危险因素(P<0.05);以饮酒、高血压、眩晕程度、病灶部位、脑白质疏松因素构建脑卒中后眩晕患者认知功能障碍风险预测模型,对危险因素进行曲线下面积(ROC)曲线分析发现,上述因素在脑卒中后眩晕患者认知功能障碍中的预测敏感度85.34%、特异度为57.33%,AUC为0.782.结论 基于饮酒、高血压、重度眩晕、病灶部位在额叶、脑白质疏松的预警模型可以有效评估脑卒中后眩晕患者发生认知功能障碍的风险.
The construction of risk warning model of cognitive dysfunction in patients with vertigo after stroke
Objective To explore the influencing factors of cognitive dysfunction in patients with vertigo after stroke,and establish a risk warning model.Methods General clinical data of 205 patients with post-stroke vertigo admitted to the department of neurology and TCM the Brain Hospital affiliated to Nanjing Medical University from April 2021 to May 2024 were retrospectively analyzed and separated into cognitive dysfunction group(n=79)and normal cognitive function group(n=126)according to whether the patients had cognitive dysfunction.The general clinical data was compared,the risk factors affecting the cognitive function of patients with vertigo after stroke were analyzed,and the risk warning model was built based on the risk factors.ROC curve was used to investigate the predictive efficacy of the model in cognitive function of patients.Results There were significant differences between the two groups in place of residence,years of education,alcohol consumption,degree of vertigo,stroke frequency,focal site,and leukoaraiosis of patients(P<0.05).Logistic regression analysis showed that drinking alcohol,hypertension,severe vertigo,lesion location in frontal lobe and leukoaraiosis were independent risk factors for cognitive dysfunction in vertigo patients after stroke(P<0.05).The risk prediction model of cognitive dysfunction in post-stroke vertigo patients was constructed based on factors such as alcohol consumption,hypertension,vertigo degree,lesion location.ROC curve analysis of risk factors showed that the predictive sensitivity,specificity and AUC of these factors were based on alcohol consumption,hypertension,severe vertigo,frontal lobe location and leukoaraiosis can 85.34%,57.33%,and 0.782 in patients with post-stroke vertigo.Conclusions Warning models effectively assess the risk of cognitive impairment in vertigo patients after stroke.

StrokeVertigoCognitive dysfunctionRisk factorsRisk warning model

徐冰泉、季灵、刘晓卫、周园园、王婷、吴君

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210029 江苏,南京医科大学附属脑科医院中医科

210029 江苏,南京医科大学附属脑科医院神经内科

210029 江苏,南京医科大学附属脑科医院信息科

脑卒中 眩晕 认知功能障碍 危险因素 风险预警模型

2025

脑与神经疾病杂志
华北地区三省二市神经病学学会协作组,河北医科大学第二医院

脑与神经疾病杂志

影响因子:0.865
ISSN:1006-351X
年,卷(期):2025.33(2)