Preparation of 1-(4-(tert-butyl)phenyl)-3-hydroxy-2-methylpyridine-4(1H)-ketone microemulsion and its control efficacy on wheat stripe rust and rice sheath blight
Preparation of 1-(4-(tert-butyl)phenyl)-3-hydroxy-2-methylpyridine-4(1H)-ketone microemulsion and its control efficacy on wheat stripe rust and rice sheath blight
In this study,the compound 1-(4-(tert-butyl)phenyl)-3-hydroxy-2-methylpyridine-4(1H)-one(hereinafter referred to as HAINU-19)was used as the active ingredient to prepare the microe-mulsion and determine its antifungal activity.First,through the screening solvents,co-solvents,and transparent,the formulation of 2.5%HAINU-19 microemulsion(mass fraction)was determined as follows:2.5%HAINU-19,15%ethanol,10%cyclohexanone,20%transparent(1601#:500#:AC-1810=3:3:1),with distilled water making up to 100%.All indicators meet national standards.The bioassay result of pot experiments showed that the protective and curative effects of 2.5%HAINU-19 microemulsion on wheat stripe rust were 100%at 1000,500,and 250-fold dilutions,and curative effects were 76.67%,81.00%,and 82.33%,respectively.The field trial results showed that the 2.5%HAINU-19 microemulsion had a control efficacy of 86.13%on rice sheath blight at a 100-fold dilution and 71.24%at a 200-fold dilution.This study can provide an experimental basis and technical support for the development and application of the antifungal compound HAINU-19.
维普
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