首页|1-(4-(叔丁基)苯基)-3-羟基-2-甲基吡啶-4(1H)-酮微乳剂的制备及其对小麦条锈病和水稻纹枯病的防治效果

1-(4-(叔丁基)苯基)-3-羟基-2-甲基吡啶-4(1H)-酮微乳剂的制备及其对小麦条锈病和水稻纹枯病的防治效果

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本文以化合物 1-(4-(叔丁基)苯基)-3-羟基-2-甲基吡啶-4(1H)-酮(以下简称为HAINU-19)为有效成分,制备微乳剂并测定其杀菌活性。首先,通过对溶剂、助溶剂、乳化剂的筛选,确定 2。5%HAINU-19 微乳剂配方(质量分数)为:2。5%HAINU-19、15%乙醇、10%环己酮、20%乳化剂(宁乳1601#:农乳500#:AC-1810=3:3:1),蒸馏水补足100%。各项指标均符合国家标准。盆栽药效试验结果表明,2。5%HAINU-19 微乳剂在稀释 1000、500 和 250 倍剂量下,对小麦条锈病的保护性防治效果均为 100%,治疗性防治效果分别为 76。67%、81。00%和82。33%。田间药效试验结果表明,2。5%HAINU-19 微乳剂对水稻纹枯病的防治效果 100 倍稀释液为 86。13%,200 倍稀释液为 71。24%。该研究可为杀菌化合物HAINU-19 的开发应用提供试验依据和技术支持。
Preparation of 1-(4-(tert-butyl)phenyl)-3-hydroxy-2-methylpyridine-4(1H)-ketone microemulsion and its control efficacy on wheat stripe rust and rice sheath blight
In this study,the compound 1-(4-(tert-butyl)phenyl)-3-hydroxy-2-methylpyridine-4(1H)-one(hereinafter referred to as HAINU-19)was used as the active ingredient to prepare the microe-mulsion and determine its antifungal activity.First,through the screening solvents,co-solvents,and transparent,the formulation of 2.5%HAINU-19 microemulsion(mass fraction)was determined as follows:2.5%HAINU-19,15%ethanol,10%cyclohexanone,20%transparent(1601#:500#:AC-1810=3:3:1),with distilled water making up to 100%.All indicators meet national standards.The bioassay result of pot experiments showed that the protective and curative effects of 2.5%HAINU-19 microemulsion on wheat stripe rust were 100%at 1000,500,and 250-fold dilutions,and curative effects were 76.67%,81.00%,and 82.33%,respectively.The field trial results showed that the 2.5%HAINU-19 microemulsion had a control efficacy of 86.13%on rice sheath blight at a 100-fold dilution and 71.24%at a 200-fold dilution.This study can provide an experimental basis and technical support for the development and application of the antifungal compound HAINU-19.

HAINU-19microemulsionformula screeningwheat stripe rustrice sheath blightcontrol efficacy

赵静杰、余海涛、张勃、赵延存、尹丰满、张羲、孙然锋

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海南大学热带农林学院,热带农林生物灾害绿色防控教育部重点实验室,海口 570228

甘肃省农业科学院植物保护研究所,兰州 730070

江苏省农业科学院植物保护研究所,南京 210014

HAINU-19 微乳剂 配方筛选 小麦条锈病 水稻纹枯病 防治效果

国家自然科学基金海南省自然科学基金

22067004321CXTD436

2024

农药学学报
中国农业大学

农药学学报

CSTPCD北大核心
影响因子:0.879
ISSN:1008-7303
年,卷(期):2024.26(4)
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