基于术后并发症及月经症状探讨宫腔镜下子宫内膜息肉切除术与宫腔镜下诊刮术在子宫内膜息肉患者中的效果对比
To investigate the effect of hysteroscopic resection of endometrial polyps and hysteroscopic curettage in patients with endometrial polyps based on postoperative complications and menstrual symptoms
任利敏 1尹保娜 2沈萌萌3
作者信息
- 1. 沁阳市妇幼保健院妇产科 河南焦作 454550
- 2. 焦作市妇幼保健院妇科 河南焦作 454000
- 3. 沁阳市妇幼保健院妇科 河南焦作 454550
- 折叠
摘要
目的 研究宫腔镜下子宫内膜息肉切除术与宫腔镜下诊刮术治疗子宫内膜息肉临床疗效及对月经症状、术后并发症的影响.方法 收集2017年1月至2023年11月期间本院医治的121例子宫内膜息肉患者,根据不同手术方法分为诊刮组(n=59)、切除组(n=62),前者行宫腔镜下诊刮术,后者行宫腔镜下子宫内膜息肉切除术.比较两组手术指标、手术前后月经症状、雌激素受体水平、生化指标[血红蛋白(Hb)、转化生长因子-β1(TGF-β1)、血管内皮生长因子(VEGF)]及并发症状况.结果 与诊刮组相比,切除组住院时间较短,出血量较少(P＜0.05);术后3个月,切除组月经经期、PBAC评分均低于诊刮组(P＜0.05);术后3个月,两组雌激素受体水平显著下降(P＜0.05);但组间相比,差异无统计学意义(P＞0.05);与诊刮组相比,切除组VEGF、TGF-β1水平较低,Hb水平较高(P＜0.05);切除组并发症发生率(1.61％)与诊刮组(8.47％)相比,差异无统计学意义(P＞0.05).结论 宫腔镜下子宫内膜息肉切除术能改善患者月经症状,降低雌激素受体、VEGF、TGF-β1水平,减少术后并发症,加快患者康复进程.
Abstract
Objective To study the clinical efficacy of hysteroscopic resection of endometrial pol-yps and hysteroscopic curettage in the treatment of endometrial polyps and its influence on men-strual symptoms and postoperative complications.Methods A total of 121 patients with endom-etrial polyps treated in our hospital from January 2017 to November 2023 were collected and di-vided into two groups according to different surgical methods:curettage group(n=59)and re-section group(n=62).The former underwent hysteroscopic curettage and the latter underwent hysteroscopic resection of endometrial polyps.Surgical indicators,menstrual symptoms before and after surgery,estrogen receptor levels,biochemical indicators[hemoglobin(Hb),transfor-ming growth factor-β1(TGF-β1),vascular endothelial growth factor(VEGF)]and complications were compared between the two groups.Results Compared with the curettage group,the dura-tion of hospital stay in the resection group was shorter and the amount of blood loss was less(P＜0.05).At 3 months after operation,the menstrual period and PBAC scores in resection group were lower than those in curettage group(P＜0.05).Three months after operation,estrogen re-ceptor levels in both groups were significantly decreased(P＜0.05).However,there was no sig-nificant difference between groups(P＞0.05).Compared with curettage group,VEGF and TGF-β1 levels were lower in resection group,and Hb levels were higher(P＜0.05).There was no significant difference in complication rate between resection group(1.61％)and curettage group(8.47％)(P＞0.05).Conclusion Hysteroscopic resection of endometrial polyps can im-prove menstrual symptoms,reduce estrogen receptor,VEGF,TGF-β1 levels,reduce postopera-tive complications,and accelerate the recovery process of patients.
关键词
诊刮术/月经症状/子宫内膜息肉/息肉切除术/并发症/宫腔镜Key words
Curettage/Menstrual symptoms/Endometrial polyps/Polypectomy/Complications/Hysteroscope引用本文复制引用
基金项目
河南省医学科技攻关联合共建项目(LHGJ20211022)
出版年
2024
NETL
NSTL
万方数据