CT图像纹理参数熵、峰度、能量、标准差对肝癌的诊断价值
The diagnostic value of CT image texture parameters entropy,kurtosis,energy and standard deviation in liver cancer
陈鹏鹏 1吴毓增1
作者信息
- 1. 中国人民解放军陆军第七十三集团军医院,福建厦门 361000
- 折叠
摘要
目的 探讨CT图像纹理参数熵、峰度、能量、标准差对肝癌的诊断价值.方法 选取医院2021年1月-2023年9月收治的疑似肝癌患者86例,全部患者均行CT检查,并行穿刺细胞学检查或手术病理检查,将穿刺细胞学检查或手术病理检查结果作为金标准,分析CT对肝癌的诊断效能;对比肝良恶性病变患者CT图像纹理参数熵、峰度、能量、标准差,绘制受试者工作曲线(ROC),分析CT图像纹理参数熵、峰度、能量、标准差对肝癌的诊断价值.结果 86例疑似肝癌患者经穿刺细胞学检查或手术病理检查提示恶性50例,占58.14％;依据经穿刺细胞学检查或手术病理检查"金标准",CT对肝癌的诊断灵敏度为(94.00％)、特异度为(94.44％)、准确度为(94.19％);肝恶性病变患者熵、峰度、标准差较良性患者高,能量较良性患者低(P＜0.05);绘制ROC曲线发现,CT图像纹理参数熵、峰度、能量、标准差单独及联合检测诊断肝癌的AUC分别为0.866、0.732、0.883、0.812、0.935,均有诊断价值,且联合检测诊断价值最高.结论 CT图像纹理诊断肝癌具有较高价值,联合测定熵、峰度、能量、标准差参数可定向评估肝癌风险,指导临床诊疗.
Abstract
Objective To investigate the diagnostic value of CT texture parameters entropy,kur-tosis,energy and standard deviation in liver cancer.Methods A total of 86 patients with suspec-ted liver cancer admitted to the hospital from January 2021 to September 2023 were selected.All patients underwent CT examination,accompanied by puncture cytology or surgical pathological examination.The results of puncture cytology or surgical pathological examination were used as the gold standard to analyze the diagnostic efficacy of CT in liver cancer.The entropy,kurtosis,energy and standard deviation of CT image texture parameters in patients with benign and malig-nant liver lesions were compared,and receiver operating curve(ROC)was drawn to analyze the diagnostic value of CT image texture parameters entropy,kurtosis,energy and standard devia-tion for liver cancer.Results Of 86 suspected patients with liver cancer,50 cases(58.14％)were malignant by puncture cytology or pathological examination.According to the"gold stand-ard"of biopsy cytology or surgical pathology,the diagnostic sensitivity,specificity and accuracy of CT for HCC were 94.00％,94.44％and 94.19％respectively.The entropy,kurtosis and standard deviation of malignant patients were higher than those of benign patients,and the ener-gy was lower than those of benign patients(P＜0.05).ROC curve was drawn and it was found that the AUC of entropy,kurtosis,energy and standard deviation of CT image texture parame-ters in diagnosis of liver cancer were 0.866,0.732,0.883,0.812 and 0.935 respectively by sin-gle and combined detection,all of which had diagnostic value,and the combined detection had the highest diagnostic value.Conclusion CT image texture has a high value in the diagnosis of liver cancer,and the combined determination of entropy,kurtosis,energy and standard deviation can be used to assess the risk of liver cancer and guide clinical diagnosis and treatment.
关键词
肝癌/电子计算机断层扫描/图像纹理/诊断价值Key words
liver cancer/Electronic computed tomography/Image texture/Diagnostic value引用本文复制引用
基金项目
厦门市医疗卫生指导性项目(2022)(3502Z20224ZD1240)
出版年
2024
NETL
NSTL
维普
万方数据