基于灰色关联结合秩和比法的药品不良反应报告质量评价研究

Research on the Quality Evaluation of Adverse Drug Reaction Reports Based on Grey Relational Analysis Combined with Rank Sum Ratio Method

秦海钰 ¹董斌 ¹王红红 ¹庞文娟 ¹陈荣红¹

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作者信息

1. 武威市药品检验检测中心,甘肃武威 733000
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摘要

目的建立基于灰色关联结合秩和比法的药品不良反应(ADR)报告质量评价模型,为ADR报告质量的合理评价提供参考.方法参照相关规定和标准,用灰色关联与秩和比相结合的方法,对某市2022年上报至国家药品不良事件监测信息系统的ADR原始报告质量进行研究评价.结果 15.4％的报告质量为中等(r(i)＞0.7326);74.6％的报告质量为合格(0.6890＜r(i)≤0.7326);1％的报告质量较差(r(i)≤0.6890),报告存在的主要问题包括ADR名称规范性欠佳、用药原因缺失、ADR分析不全面等.结论灰色关联度结合秩和比的方法用于评价ADR报告质量,能综合两种方法的优势、使结果更为合理.

Abstract

Objective To develope a quality evaluation model for adverse drug reaction(ADR)re-ports based on a combination of Grey Relational Analysis and Rank-Sum Ratio methods,witch can provid a reference for reasonable assessment of ADR report quality.Methods evaluating the quality of ADR original reports submitted to the National Adverse Drug Event Monitoring Infor-mation System from a certain city in 2022,followed relevant regulations and standards and used a combination of Grey Relational Analysis and Rank-Sum Ratio methods.Results 15.4％of the reports had medium quality(r(i)＞0.7326);74.6％had acceptable quality(0.6890＜r(i)≤0.7326);and 1％had poor quality(r(i)≤0.6890).Main issues included inadequate standardi-zation of ADR names,missing medication reasons,and incomplete ADR analysis.Conclusion Combining Grey Relational Analysis with Rank-Sum Ratio methods to evaluat ADR report quali-ty effectively integrates the advantages of both methods,resulting in a more reasonable outcome.

关键词

药品不良反应/报告质量/灰色关联度法/秩和比法

Key words

Adverse Drug Reactions/Report Quality/Grey Relational Analysis/Rank-Sum Ratio

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出版年

2024

青岛医药卫生

青岛市医学会

青岛医药卫生

影响因子：0.693

ISSN：1006-5571

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