重症难治性支原体肺炎混合感染病儿的临床特点
Clinical characteristics of children with severe refractory Mycoplasma pneumonia with mixed infections
刘田田 1王金菊 1梁艳龙 1张丽娉 1解童玲 1孙广荣1
作者信息
- 1. 青岛大学附属妇女儿童医院呼吸科,山东青岛 266032
- 折叠
摘要
目的 探讨儿童重症难治性支原体肺炎混合感染的临床特点.方法 以82例重症难治性支原体肺炎病儿为研究对象,通过回顾性分析病儿的临床资料,对比混合感染组和单纯感染组的发热及住院时间、炎性指标、肺内外并发症及黏液痰栓发生率等差异.结果 与单纯感染组相比,混合感染组病儿发热时间、中性粒细胞比例、C反应蛋白(CRP)、铁蛋白、肺坏死发生率、肝功能损害发生率和黏液栓发生率等均明显升高,差异均有统计学意义(Z=1.941～2.492,t=4.577,x2=4.209、6.964,P＜0.05).结论 重症难治性支原体肺炎合并混合感染后,发热时间延长,全身炎症反应加重,肺内外并发症、黏液栓的发生率增加.
Abstract
Objective To study the clinical characteristics of children with severe refractory Mycoplasma pneumonia with mixed infections.Methods We retrospectively analyzed the clinical data of 82 children with severe refractory Mycoplasma pneu-monia.Children with mixed infections and those with single infections were compared for fever duration,the length of hospital stay,inflammatory indicators,and the incidence rates of pulmonary and extrapulmonary complications and mucus plugging.Re-sults Compared with those with single infections,children with mixed infections had a significantly longer duration of fever,a sig-nificantly higher neutrophil percentage,significantly higher levels of C-reactive protein and ferritin,and significantly higher per-centages of necrotizing pneumonia,liver function impairment,and mucus plugging(Z=1.941-2.492,t=4.577,x2=4.209,6.964,P＜0.05).Conclusion Children with severe refractory Mycoplasma pneumonia with mixed infections are more likely to have a prolonged fever and more severe systemic inflammation and develop pulmonary and extrapulmonary complications and mucus plug-ging.
关键词
肺炎,支原体/同时感染/儿童Key words
pneumonia,Mycoplasma/coinfection/child引用本文复制引用
基金项目
青岛市科技惠民项目(21-1-4-rkjk-18-nsh)
出版年
2024
国家科技期刊平台
NSTL
万方数据