DPMAS+PE联合131I治疗甲亢性重度高胆红素血症1例并文献复习
DPMAS+PE combined with 131I in the treatment of hyperthyroidism-induced severe hyperbilirubinemia:a case report and literature re-view
王玉荣 1王凤 2江晨 3陈栋 4陈立震 2辛永宁1
作者信息
- 1. 南京医科大学附属青岛临床医学院感染性疾病科,山东青岛 266011
- 2. 青岛市市立医院感染性疾病科
- 3. 青岛市市立医院病理科
- 4. 青岛市市立医院核医学科
- 折叠
摘要
目的 探讨双重血浆分子吸附系统(DPMAS)联合血浆置换(PE)和131I治疗甲状腺功能亢进(甲亢)性重度高胆红素血症的临床效果.方法 报告1例甲亢性重度高胆红素血症病人,结合相关的文献复习,总结其临床特点及诊治经验.结果 本文病人在内科综合治疗的基础上,给予DPMAS联合PE和131I治疗,病人甲状腺功能及肝功能明显好转.结论 甲亢性重度高胆红素血症的诊断和治疗较为困难,DPMAS+PE人工肝治疗技术结合131I可能是在内科综合治疗基础上治疗甲亢性重度高胆红素血症的合理选择.
Abstract
Objective To investigate the clinical effectiveness of double plasma molecular adsorption system(DPMAS)com-bined with plasma exchange(PE)and 131I therapy in the treatment of hyperthyroidism with severe hyperbilirubinemia.Methods We reported a case of hyperthyroidism-induced severe hyperbilirubinemia,and reviewed related literature to summarize its clinical characteristics and diagnosis and treatment experience.Results After comprehensive routine treatment as well as DPMAS combined with PE and 131I therapy,the thyroid function and liver function of the patient were significantly improved.Conclusion Severe hyperbilirubinemia due to hyperthyroidism is difficult to diagnose and treat,and DPMAS+PE/artificial liver systems+131I treatment may be an appropriate complement to comprehensive routine treatment.
关键词
甲状腺功能亢进症/肝功能衰竭/高胆红素血症/肝,人工/碘同位素/治疗结果/病例报告Key words
hyperthyroidism/liver failure/hyperbilirubinemia/liver,artificial/iodine isotopes/treatment outcome/case reports引用本文复制引用
基金项目
国家自然科学基金面上项目(32171277)
国家自然科学基金青年基金(82100618)
中国博士后科学基金面上项目(2021M701820)
出版年
2024
国家科技期刊平台
NSTL
万方数据