Objective To investigate the clinicopathological features and key diagnostic points of invasive lobular carcinoma(ILC)of the breast with gastric metastasis.Methods One ILC patient with gastric metastasis was analyzed in terms of clinico-pathological features,immunophenotypes,and clinical manifestations,and related articles were reviewed.Results A female pa-tient,aged 45 years,who had a previous history of poorly differentiated gastric adenocarcinoma was found to have a mass in the left breast one year later and was diagnosed with ILC by aspirationbiopsy.Based on medical history,aspirationbiopsy of gastric mucosa and breast,and immunohistochemistry,the patient was finally diagnosed with ILC with gastric metastasis.Conclusion ILC with gastric metastasis is relatively rare.The possibility of gastric metastasis of ILC should be considered when a patient with the history of ILC is found to have low-adhesion gastric carcinoma without carcinoma in situ,and gastroscopy,biopsy,and immunohis-tochemical staining can be used for differential diagnosis.
关键词
乳腺肿瘤/肿瘤转移/胃肿瘤/诊断,鉴别/免疫组织化学/病例报告
Key words
breast neoplasms/neoplasm metastasis/stomach neoplasms/diagnosis,differential/immunohistochemistry/case reports