Objective To establish a nomogram based on CT radiomics in differential diagnosis of focal cryptogenic or-ganizing pneumonia(FCOP)and lung adenocarcinoma(LA).Methods The CT and clinical data of 77 patients with FCOP and 77 patients with LA were collected retrospectively.The patients were randomly divided into training set(n= 106)and verification set(n=48)according to 7∶3.Radiomics features are extracted by A.K.software and constructed ra-diomics signature after the screening.Then we constructed the nomogram,and evaluated the diagnostic efficiency,internal validation,calibration assessment and clinical usefulness of the model.Results The eleven highly correlated radiomics features were screening to construct radimomics signature.The AUC of the nomogram of CEA and radiomics signature in the training group and the verification group was 0.84.And the nomogram showed good diagnostic efficiency,internal vali-dation and clinical usefulness of the model.Conclusion The nomogram established by CT radiomics features has good performance to distinguish FCOP and LA.
维普
万方数据