Effect of early intensive antihypertensive treatment on neurological function and short-term prognosis of pa-tients with hypertensive intracerebral hemorrhage
Effect of early intensive antihypertensive treatment on neurological function and short-term prognosis of pa-tients with hypertensive intracerebral hemorrhage
Objective To explore the influence of early intensive antihypertensive treatment on neurological function and short-term prognosis of patients with hypertensive intracerebral hemorrhage(HICH).Methods Totally 150 pa-tients with HICH were selected and randomly divided into esearch group and rcontrol group with 75 cases in each.The control group was received conventional antihypertensive treatment,and the research group was received early intensive antihypertensive treatment.The volume of cerebral edema was measured,and the national institutes of health stroke scale(NIHSS)scores on the 3rd,7th,and 14th day of treatment were evaluated,respectively.The hematoma expansion rate within 3 days between the two groups was compared,and the clinical prognosis was evaluated by the modified Rankin scale(mRS)on the 90th day after treatment.Results Within 3 days of treatment,the hematoma expansion rate in the research group was 6.67%,which was significantly lower than 21.33%in the control group(χ2=7.75,P＜0.05).There was no statistically significant difference in the volume of brain edema between the two groups on 3th,7th,and 14th day after treatment(t=1.10,0.57,1.37,P＞0.05).On the 7th and 14th day after treatment,the NIHSS score of the research group was significantly lower than that of the control group(t=3.95,3.24,P＜0.05).The 90-day prognosis evaluation showed that the good prognosis rate of the research group was significantly higher than that of the control group(χ2= 4.08,P＜0.05).Conclusion Early intensive antihypertensive treatment can reduce the incidence of hematoma enlarge-ment in HICH patients,without increasing the volume of peripheral brain edema,and can improve neurological function and short-term prognosis.
维普
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