全科医学临床与教育2024,Vol.22Issue(1) :36-40.DOI:10.13558/j.cnki.issn1672-3686.2024.001.010

NoSAS评分在识别深度镇静支气管镜检查期间低氧血症高风险群体中的应用

Application of NoSAS score in identifying high-risk groups for hypoxemia during deep sedation bronchoscopy

祝丁 周家明 张雯
全科医学临床与教育2024,Vol.22Issue(1) :36-40.DOI:10.13558/j.cnki.issn1672-3686.2024.001.010

NoSAS评分在识别深度镇静支气管镜检查期间低氧血症高风险群体中的应用

Application of NoSAS score in identifying high-risk groups for hypoxemia during deep sedation bronchoscopy

祝丁 1周家明 2张雯3
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作者信息

  • 1. 310022 浙江杭州,浙江省肿瘤医院综合内科;中国科学院杭州医学研究所
  • 2. 310022 浙江杭州,浙江省肿瘤医院内镜科;中国科学院杭州医学研究所
  • 3. 310022 浙江杭州,浙江省肿瘤医院麻醉科;中国科学院杭州医学研究所
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摘要

目的 探索NoSAS评分在识别深度镇静支气管镜检查期间低氧血症高风险群体中的应用价值.方法 选择接受深度镇静支气管镜检查的293 例患者作为研究对象.据NoSAS评分标准分为阻塞性睡眠呼吸暂停综合征(OSAS)高风险组和低风险组.比较两组患者在深度镇静支气管镜期间低氧血症等心肺不良事件的发生率和气道干预率.对发生低氧血症的影响因素进行单因素分析和多因素logistic回归分析.结果 与OSAS低风险组相比,高风险组发生低氧血症、严重低氧血症、气道干预(托下颌、提高氧流量、储氧面罩通气)的频率更高,差异均有统计学意义(χ2分别=8.47、5.51、14.36、4.52、8.48,P均<0.05).logistic多因素分析显示OSAS高风险组较低风险组显著增加深度镇静支气管镜检查期间发生低氧血症的风险(OR=2.38,95%CI 1.28~4.43,P<0.05).结论 NoSAS评分有助于识别深度镇静支气管镜检查期间发生低氧血症高风险的群体,为预防及干预低氧血症提供重要依据.

Abstract

Objective To explore the application value of NoSAS score in identifying high-risk groups for hypoxemia during deep sedation bronchoscopy.Methods Totally 293 patients who underwent deep sedation bronchoscopy were se-lected as the subjects.Patients were divided into obstructive sleep apnea syndrome(OSAS)high-risk group and OSAS low-risk group according to NoSAS score.The incidence of cardiopulmonary adverse events such as hypoxemia and air-way intervention rates between two groups of patients during deep sedation bronchoscopy were compared.Univariate analy-sis and multivariate logistic regression analysis were conducted on the influencing factors of hypoxemia.Results Com-pared with the low-risk group,the high-risk group had a higher frequency of hypoxemia,severe hypoxemia,and airway intervention(jaw lift,increase the flow of oxygen,bag-mask ventilation),and the differences were statistically significant(χ2=8.47,5.51,14.36,4.52,8.48,P<0.05).Logistic multivariate analysis further showed that the high-risk group signifi-cantly increased the risk of hypoxemia during deep sedation bronchoscopy when compared to the low-risk group,with sta-tistical significance(OR= 2.38,95%CI 1.28-4.43,P<0.05).Conclusion The NoSAS score helps to identify high-risk groups for hypoxemia during deep sedation bronchoscopy,and provid a valuable evidence for active prevention and inter-vention of hypoxemia.

关键词

NoSAS评分/阻塞性睡眠呼吸暂停综合征/深度镇静/支气管镜/低氧血症

Key words

NoSAS/obstructive sleep apnea syndrome/deep sedation/bronchoscopy/hypoxemia

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出版年

2024
全科医学临床与教育
浙江大学

全科医学临床与教育

影响因子:0.63
ISSN:1672-3686
参考文献量9
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