摘要
目的 探讨八正散加减联合体外冲击波碎石术(ESWL)治疗直径≥1.5 cm肾下盏结石(LPRS)患者的疗效.方法 选取直径≥1.5 cm LPRS患者82 例,随机分成研究组(n=41)和对照组(n=41).对照组给予ESWL,研究组给予八正散加减联合ESWL,比较两组疗效、症状积分、生活质量及并发症.结果 研究组总有效率高于对照组(97.56%vs.80.49%),差异有统计学意义(P＜0.05);治疗后两组腰痛、血尿、尿潴留、肾绞痛症状积分均降低(t分别=45.83、30.65、59.23、44.91;27.80、20.90、39.78、32.16,P均＜0.05),研究组较对照组更低(t分别= 17.57、8.79、19.45、17.12,P均＜0.05);治疗后两组躯体健康、社会功能、心理健康、物质生活条件等生活质量评分均提高(t分别=19.39、20.46、22.71、22.60;15.38、17.03、18.69、19.72,P均＜0.05),研究组较对照组更高(t分别=4.62、3.89、4.61、4.68,P均＜0.05);研究组并发症发生率低于对照组(4.88%vs.24.39%),差异有统计学意义(χ2 =6.25,P＜0.05).结论 采用八正散加减联合ESWL治疗直径≥1.5 cm LPRS患者,可提高临床疗效,降低临床症状积分,改善生活质量,减少并发症.
Abstract
Objective To explore the effect of Bazhengsan modified and subtracted combined with extracorporeal shock wave lithotripsy(ESWL)in lower pole renal stone(LPRS)patients with diameter≥1.5 cm.Methods A total of 82 cases LPRS patients with diameter≥1.5cm were selected and randomely divided into the research group(41 cases)and the control group(41 cases).The control group was given ESWL,the research group was treated with modified Ba-zhengsan combined with ESWL.The clinical efficacy,clinical symptom scores,quality of life and complications were com-pared between the two groups.Results Compared with the control group,the total effective rate of treatment in the re-search group(97.56%vs.80.49%)was higher(P＜0.05).After treatment,the symptom scores of low back pain,hematu-ria,urinary retention and renal colic in two groups were decreased(t=45.83,30.65,59.23,44.91,27.80,20.90,39.78,32.16,P＜0.05),and the these indexes in research group were lower than the control group(t=17.57,8.79,19.45,17.12,P＜0.05).After treatment,the scores of the quality of life,such as physical health,social function,mental health,material living conditions in two groups were increased(t=19.39,20.46,22.71,22.60,15.38,17.03,18.69,19.72,P＜0.05),and these indexes in the research group were higher than the control group(t=4.62,3.89,4.61,4.68,P＜0.05).The complica-tion rate of the research group was lower than that of the control group(4.88%vs.24.39%),the difference was statistical-ly significant(χ2=6.25,P＜0.05).Conclusion Bazhengsan combined with ESWL can improve the clinical efficacy,re-duce the clinical symptom score,improve the quality of life and reduce the incidence of complications in LPRS patients with diameter≥1.5cm.
万方数据