Objective To investigate the molecular subtype differences between mass-type and non-mass-type breast cancer and explore the relationship between mammographic features and molecular subtype.Methods The clinical,pathologic and imaging data of 210 mass-type and 162 non-mass-type breast cancer cases were analyzed retrospectively to evaluate the potential associations between imaging features and molecular subtypes in these two groups.Results Non-mass type lesions are inclined to occurs in younger patients and with a higher rate of non-invasive carcinoma.The mass-type group has the opposite characteristics.Higher incidence rate of Luminal B can be observed in mass-type and Luminal HER-2 incidence rate was higher in non-mass-type.In mass type group,some mammographic features such as asymmetry accompaniment rate had statistical significance.In non-mass type group,incidence rates of architectural dis-tortion and calcification,morphology of calcification also had statistical significances.Conclusion There are some dif-ferences in clinical,pathologic characteristics and molecular subtypes between mass-type and non-mass-type group.Some mammographic features were proved to have discrepancies among several breast cancer molecular subtypes.It may be valuable in treatment selection and prognosis prediction.
关键词
肿块型乳腺癌/非肿块型乳腺癌/乳腺X线摄影/免疫组织化学/乳腺癌分子分型
Key words
mass-type breast cancer/non-mass-type breast cancer/X-ray mammography/immunohistochemis-try/molecular subtypes of breast cancer
维普
万方数据