Predictive value of preoperative intravascular ultrasound calcification characteristics for coronary in-stent reste-nosis in patients with non-ST-segment elevation acute coronary syndrome after PCI
Predictive value of preoperative intravascular ultrasound calcification characteristics for coronary in-stent reste-nosis in patients with non-ST-segment elevation acute coronary syndrome after PCI
Objective To establish a prediction model of preoperative intravascular ultrasound calcification characteris-tics for coronary in-stent restenosis(ISR)in patients with non-ST-segment elevation acute coronary syndrome(NSTE-ACS)after PCI and explore its predictive value.Methods One hundred and forty-six patients with NSTE-ACS who un-derwent percutaneous coronary intervention(PCI)were retrospectively selected as the study objects and divided into nor-mal group(89 cases)and restenosis group(57 cases)according to the prognosis of coronary ISR.Preoperative intravas-cular ultrasound calcification characteristics and other clinical data of patients were collected,and univariate analysis was conducted to determine the relevant factors affecting coronary ISR after PCI.The independent risk factors were screened by binary logistic regression analysis,and the prediction model was established based on the independent risk factors.Re-ceiver operating characteristic(ROC)curve was drawn and predictive value was evaluated.Results The characteristics of intravascular ultrasound calcification such as large arc of coronary calcification,long length of calcification and superfi-cial calcification type were independent risk factors affecting coronary ISR after PCI(OR=1.44,1.03,2.93,P＜0.05),and the area under the ROC curve(AUC)established by the three indexes was 0.88.Conclusion The characteristics of preoperative intravascular ultrasound calcification,such as large arc of intracoronary calcification,long length of calcifi-cation and superficial calcification are independent risk factors for coronary ISR after PCI.Therefore,the construction of a prediction model has high predictive value for the occurrence of coronary ISR after PCI.
关键词
非ST段抬高型急性冠脉综合征/血管内超声/再狭窄/钙化特征/预测模型
Key words
non-ST-segment elevation acute coronary syndrome/intravascular ultrasound/restenosis/calcifica-tion characteristics/prediction model
维普
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