摘要
目的 探究中青年与老年脑梗死患者临床特点及颈部血管超声(CVUS)、CT血管造影(CTA)、磁共振血管造影(MRA)特征.方法 回顾性分析103例脑梗死患者临床资料,所有患者均行CVUS、CTA及MRA检查,按照患者年龄分为中青年组(18～60岁)53例和老年组(＞60岁)50例.比较两组患者一般资料、临床特征及影像学(CVUS、CTA、MRA)特征.结果 中青年组年龄、总胆固醇(TC)、甘油三酯(TG)水平、糖尿病及高血脂占比均低于老年组,高学历、吸烟、饮酒、高血压占比均高于老年组(t分别=20.14、2.45、4.10,x2分别=5.00、7.59、12.62、4.50、6.79、3.90,P均＜0.05);中青年组意识障碍、语言障碍、逐渐发作、活动时发病发生率均低于老年组,且发病时间短于老年组(x2分别=4.21、4.43、4.56、5.30,t=4.37,P均＜0.05);CVUS及MRA显示,中青年组中未见明显异常占比高于老年组(x2分别=4.50、5.13,P均＜0.05),CTA显示,中青年组中纤维核心混合斑块占比高于老年组(x2=5.83,P＜0.05).结论 中青年脑梗死患者起病急,合并基础病较少,而老年脑梗死患者基础病较多,症状严重,中青年脑梗死患者血管病变程度低于老年患者.
Abstract
Objective To explore the clinical characteristics and cervical vascular ultrasound(CVUS),CT angiogra-phy(CTA)and magnetic resonance angiography(MRA)features in young and middle-aged and elderly patients with ce-rebral infarction.Methods The clinical data of 103 patients with cerebral infarction were retrospectively analyzed.All patients underwent CVUS,CTA and MRA examinations.According to the age of patients,the patients were divided into young and middle-aged group(18-60 years old,53 cases)and elderly group(＞60 years old,50 cases).The general da-ta,clinical characteristics and imaging features of CVUS,CTA,MRA were compared between both groups.Results The age,TC,TG and proportions of diabetes mellitus and hyperlipidemia in young and middle-aged group were lower than those in elderly group,while the proportions of high education,smoking,drinking and hypertension were higher than those in elderly group(t=20.14,2.45,4.10,x2=5.00,7.59,12.62,4.50,6.79,3.90,P＜0.05).The incidence rates of con-sciousness disorder,language disorder,progressive attack and disease onset during activity in young and middle-aged group were lower,and the onset time was shorter than that in elderly group(x2=4.21,4.43,4.56,5.30,t=4.37,P＜0.05).CVUS and MRA showed that the proportion of no obvious abnormalities was higher in young and middle-aged group than that in elderly group(x2=4.50,5.13,P＜0.05),and CTA revealed that the proportion of fibrous core mixed plaques was higher than that in elderly group(x2=5.83,P＜0.05).Conclusion Young and middle-aged patients with cerebral infarction have acute onset and few underlying diseases,while elderly patients with cerebral infarction have more underly-ing diseases and more severe symptoms.The degree of vascular lesions in young and middle-aged patients with cerebral infarction is milder than that in elderly patients.
维普
万方数据