Objective To investigate the clinical application value of computed tomographic pulmonary angiography(CTPA)in the assessment of the changes of right ventricular function in patients with acute pulmonary embolism(APE).Methods We systematically retrieved the clinical controlled studies that exploring the evaluation of right ven-tricular function in patients with APE by CTPA from January 2000 to February 2023,which were published in PubMed,Embase,Web of Science,Cochrane,WanFang,VIP,and CNKI.Literature screening and data extraction were performed in-dependently by two investigators.Included articles were assessed for bias using the Newcastle-Ottawa scale.This meta-analysis was conducted using Review Manager version 5.4 software.Results Meta analysis indicated that ratio of the maximum diameter of right ventricle to left ventricle(RVd/LVd)(SMD=1.25,95%CI:0.94-1.56,P＜0.05),ratio of the maximum cross-sectional area of right ventricle to left ventricle(SMD=0.80,95%CI:0.71-0.89,P＜0.05),ratio of the volume of right ventricle to left ventricle(SMD=1.42,95%CI:0.44-2.40,P＜0.05),and ratio of the maximum distance between the right ventricle and left ventricle(SMD=0.91,95%CI:0.57-1.25,P＜0.05)of the APE group were signifi-cantly higher than those of the non-APE group.There was significant difference of RVd/LVd in central APE group com-pared with peripheral APE group(SMD=1.73,95%CI:0.95-2.51,P＜0.05).Conclusion CTPA may be helpful for the evaluating the right ventricular function in patients with APE.
维普
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