Analysis of the expression level of blood glucose variability related indicators in patients with severe pulmonary tuberculosis and its predictive efficiency on poor prognosis
Analysis of the expression level of blood glucose variability related indicators in patients with severe pulmonary tuberculosis and its predictive efficiency on poor prognosis
Objective To investigate the predictive effect of blood glucose variability on poor prognosis in patients with severe pulmonary tuberculosis.Methods A total of 86 patients with severe pulmonary tuberculosis were divided in-to death group(n=23)and survival group(n=63)according to the prognosis.The APACHE Ⅱ scores and blood glucose variability indexes of the two groups were compared,and the risk factors of patients with poor prognosis(death)and the predictive efficiency of serum GluAve,GluSD and GluCV on poor prognosis were analyzed.Results The APACHE Ⅱ score,serum GluSD and GluCV levels in death group were higher than those in the survival group(t=4.66,3.10,3.19,P<0.05).Further multivariate logistic regression analysis showed that serum GluSD and GluCV levels were both risk factors for poor prognosis in patients(OR=3.13,17.70,P<0.05),and the area under the curve(AUC)of their com-bined prediction of poor prognosis in severe pulmonary tuberculosis patients was 0.81,with a sensitivity of 78.26％and a specificity of 77.78％.Conclusion There are significant differences in the related indexes of blood glucose variability in patients with severe pulmonary tuberculosis with different prognosis.The combination of GluSD and GluCV has high effi-ciency in predicting poor prognosis in patients with severe pulmonary tuberculosis.
关键词
重症肺结核/血糖变异性/预后不良/预测效能
Key words
severe pulmonary tuberculosis/blood glucose variability/poor prognosis/predictive efficiency
维普
万方数据