Objective To investigate the value of lacrimal gland prominence and MRI fat quantitative analysis(IDE-AL-IQ)in the diagnosis of thyroid associated ophthalmopathy(TAO).Methods Clinical datas of 38 TAO patients(TAO group)and 38 healthy volunteers(control group)were retrospectively analyzed.Lacrimal gland prominence,fat fraction(FF)and relative fat fraction(rFF)were measured to analyze the differences between two groups.The receiver operating characteristic(ROC)curve was used to analyze the diagnostic efficacy of lacrimal gland protrusion,FF,rFF single and combined tests on TAO.Results The lacrimal gland prominence,FF and rFF in TAO group were higher than those in control group(t=8.18,6.10,Z=-5.66,P＜0.05),The AUC of lacrimal gland prominence combined with FF for diagnosing TAO was 0.88,specificity was 90.80%,sensitivity was 73.70%.Conclusion The lacrimal gland prom-inence and FF of TAO patients are higher than those of control group.The combination of lacrimal gland prominence and FF is helpful for the diagnosis of TAO patients with high clinical value.
维普
万方数据