Objective To analyze the diagnostic value of computed tomography(CT)and magnetic resonance imaging(MRI)in the scope of tumor invasion in the head and face squamous cell carcinoma(SCC).Methods Totally 64 pa-tients with squamous cell carcinoma of the head and face were selected as the study subjects.All underwent CT or MRI examinations,and the collected CT and MRI imaging data were analyzed.The internal consistency coefficient was used to evaluate the consistency between CT,MRI,and pathological examination in determining the extent of tumor invasion.Results Among 22 patients underwent routine CT scans,16 cases(84.21%)were subcutaneous fat layer disruption,and pathological examination revealed 19 cases of subcutaneous fat layer disruption.Kappa value for CT and pathological examination in diagnosing the extent of tumor invasion was 0.69,with moderate consistency(P<0.05).In 42 patients who underwent MRI scans,34 cases(97.14%),24 cases(92.31%),and 15 cases(75.00%)were subcutaneous fat layer disruption,involvement of the skull bone,and involvement of the dura mater,respectively.The pathological examination showed subcutaneous fat layer disruption,involvement of the skull bone,and involvement of the dura mater were 35,26,and 20 cases,respectively.Kappa value for MRI and pathological examination in diagnosing the extent of tumor invasion was 0.79,with good consistency(P<0.05).Conclusion Head and face squamous cell carcinoma has certain character-istics in MRI and CT imaging,which can be combined with clinical manifestations for preoperative diagnosis.MRI has better advantages in evaluating the scope of tumor invasion,and can be used as an imaging measure to evaluate the prog-ress of the disease before treatment.