This study investigates the influence of the arrangement of piers with different heights on the seismic vulnerability of the sharp-radius curved girder bridge.For the second continuous unit of a ramp of an interchange,there are five piers with different heights,with the height of the two end piers kept constant,the three intermediate piers are varying in heights.Three ways of arranging the three intermediate piers were compared,including arranging the three piers in the sequence of heights,arranging the highest pier in the center,and arranging the lowest pier in the center.Concentrated hinge-fiber models of the piers of the curved bridge with intentional damages induced by the flexure-shear-torsion interactions were built in SeismoStruct,considering the three different pier arrangements.To accommodate the geological conditions of the bridge site,50 seismic waves that match the characteristics of terrain Ⅲ were input to study the seismic vulnerability of the piers and bearings.It is concluded that when the piers are arranged in three different ways,the complete damage probabilities of the medium pier and high pier primarily subjected to the flexural forces are relatively low in an earthquake event,while the complete damage probabilities of low piers subjected to the interaction of flexural and shear forces are higher under strong earthquake.It is suggested to enhance the seismic performance of the low piers with a degree.Arranging the lowest pier in the center would increase the damage probability of the pier.It is better not to select this way of pier arrangement in the seismic design,but to optimize the pier-girder connection is justified.Piers are more likely to be damaged than the bearings,considering the pier height variation.