摘要
目的:探究济南地区人群幽门螺杆菌的感染状况以及幽门螺杆菌感染与肝功、血糖、血脂的相关性,为临床诊断和治疗幽门螺杆菌感染提供参考依据.方法:收集2022年9月1日-2022年12月31日在山东中医药大学附属医院进行健康体检的5344例体检者的基本信息以及幽门螺杆菌抗体检测结果和生化指标.采用SPSS22.0进行数据的统计学分析.结果:幽门螺杆菌感染阳性率为39.85％,其中以Ⅰ型幽门螺杆菌感染为主,达到24.94％;幽门螺杆菌感染与性别差异无关;不同年龄段的幽门螺杆菌感染差异有统计学意义,Ⅱ型HP组中中年人群所占比例高于阴性对照组和Ⅰ型HP组,而青年人群所占比例低于其余两组;幽门螺杆菌感染者的ALB、GLU、TG、CHOL、LDL-C水平与阴性对照者比较差异有统计学意义,Ⅰ型HP组和Ⅱ型HP组的ALB水平均低于阴性对照组,而GLU、TG、CHOL、LDL-C水平均高于阴性对照组;HDL-C水平在不同组间差异无统计学意义.结论:幽门螺杆菌感染以Ⅰ型为主,感染情况与性别差异无明显相关性,幽门螺杆菌感染人群的ALB水平低于健康人群,而GLU、TG、CHOL、LDL-C水平高于健康人群,Ⅰ型与Ⅱ型幽门螺杆菌感染人群间的ALB、GLU、TG、CHOL、HDL-C、LDL-C水平无明显差异.
Abstract
Objective:To explore the infection status of Helicobacter pylori in Jinan and the correlation between H.pylori infection and liver function,blood glucose,blood lipids,and provide reference for the clinical diagnosis and treatment.Methods:A total of 5344 patients who underwent physical examination in the Affiliated Hospital of Shandong University of Traditional Chinase Medicine from September 1,2022 to December 31,2022 were studied.We collected the patients'basic information,H.pylori antibody detection results and biochemical results.SPSS22.0 was used for statistical analysis of the data.Results:The positive rate of H.pylori infection was 39.85％,of which the type Ⅰ was the main infection type,reaching 24.94％.The infection of H.pylori was not associated with sex difference.The difference of H.pylori infection in different age groups was significant.The proportion of middle-aged people in the type Ⅱ HP group was higher than that in the negative control group and type Ⅰ HP group,while the proportion of young people was lower than in the other two groups.The levels of ALB,GLU,TG,CHOL,LDL-C in patients infected with H.Pylori were statistically significantly different from those in the negative control.The level of ALB in the type Ⅰ HP group and type Ⅱ HP group was lower than that in the negative control group,while the levels of GLU,TG,CHOL,and LDL-C were higher than those in the negative control group.The level of HDL-C was not statistically significant between different groups.Conclusion:The type Ⅰ was the main infection type of H.pylori The infection status was not associated with sex difference.The level of ALB in people infected with H.pylori was lower than that in healthy people,while the levels of GLU,TG,CHOL,LDL-C were higher than those in healthy people.There were no significant difference in the levels of ALB,GLU,TG,CHOL,HDL-C,and LDL-C between people infected with the type Ⅰ H.pylori and the type Ⅱ H.pylori.
维普
万方数据