Objective:To explore the analysis of related diseases of EB virus infection in A Third-class Hospital.Methods:A retrospective method was used to select 503 EBV-DNA positive cases in A Third-class Hospital from November 2021 to February 2023,and analyze the proportion of various diseases and the proportion of hematopoietic stem cells before and after hematopoietic stem cell transplantation.Results:Among the 503 EBV-DNA positive cases,include 145 patients with nasopharyngeal carcinoma accounted for 28.83％of the total,69 patients with lymphoma accounted for 13.72％of the total,and 156 patients with hematological malignancies accounted for 31.01％of the total,12 patients with Infectious mononucleosis accounted for 2.39％of the total,37 patients with kidney transplantation accounted for 7.36％of the total,21 patients with autoimmune system diseases accounted for 4.17％of the total,and 63 patients with other diseases accounted for the total 12.52％.Patients with hematological malignancies include acute non-lymphocytic leukemia accounting for 36.54％,acute lymphocytic leukemia accounting for13.46％,thalassemia accounting for 28.21％,aplastic anemia accounting for 12.18％,myelodysplastic syndrome accounting for 5.77％,and other blood diseases accounting for 3.85％.Among 156 cases of hematological diseases,140 cases underwent hematopoietic stem cell transplantation.Among them,86 cases were negative before EBV-DNA transplantation and positive after transplantation,18 cases were positive before transplantation and negative after transplantation,36 cases were positive after transplantation and before transplantation.Conclusion:Hematological malignancies account for the highest proportion of EBV-DNA positive cases,and the infection rate after transplantation is higher than before transplantation.Nasopharyngeal carcinoma and lymphoma accounted for the second and third EBV-DNA positives,indicating that the occurrence of the two diseases has a great correlation with EBV.
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