首页|山东某医院沙门氏菌流行特征及血清学分型研究

山东某医院沙门氏菌流行特征及血清学分型研究

Study on epidemic characteristics and serological typing of Salmonella in a hospital in Shandong Province

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目的:了解我院腹泻病例中沙门氏菌的感染情况和血清型,为本地区有效防治沙门氏菌感染、制定预防策略及临床用药等提供科学依据.方法:选取山东省某县三级乙等医院的833例疑似细菌性腹泻病例的粪便标本进行细菌培养及分离鉴定,并分析其临床分布特征.结果:833例中共检出40例(4.8%)沙门氏菌感染,不同季节阳性率差异有统计学意义(x2=8.428,P<0.05);40例沙门氏菌感染患者的性别、年龄、职业、户籍及就诊前抗生素服用情况与是否检出沙门氏菌之间的差异不具有统计学意义(P>0.05);与单一感染相比,混合感染的腹痛、恶心、呕吐和发热的发生率较高,且差异具有统计学意义(P<0.05);分离的沙门氏菌共有8种血清型,主要为肠炎沙门氏菌(30%)和鼠伤寒沙门氏菌(50%).结论:沙门氏菌感染多在夏秋季节发病,可针对高发季节对重点人群进行健康宣教,制定行为干预及相应的治疗措施,降低沙门氏菌感染发病率.
Objective:To understand the infection situation and serotype of salmonella in diarrhea cases in our hospital,so as to provide scientific basis for effective prevention and treatment of salmonella infection,formulation of prevention strategy and clinical medication in this area.Methods:The fecal samples of 833 suspected bacterial diarrhea cases from a third-class hospital in Shandong province were cultured,isolated and identified,and their clinical distribution characteristics were analyzed.Results:A total of 40 cases(4.8%)of salmonella infection were detected in 833 cases,and the positive rate was statistically significant in different seasons(x2=8.428,P<0.05).There was no significant difference in sex,age,occupation,household registration,antibiotic use before treatment and salmonella detection in 40 patients with salmonella infection(P>0.05).Compared with single infection,the incidence of abdominal pain,nausea,vomiting and fever in mixed infection was higher,and the difference was statistically significant(P<0.05).There are 8 serotypes of salmonella isolated,mainly Salmonella enteritis(30%)and Salmonella typhimurium(50%),which are the dominant serotypes.Conclusion:Salmonella infection mostly occurs in summer and autumn in a county of Shandong province.Health education can be carried out for key groups in the high incidence season,behavioral intervention measures can be made to reduce the incidence of salmonella infection and timely treatment of patients with salmonella infection.

SalmonellaDiarrheaEpidemic characteristicsSerotypeHealth education

张冠军、范得普、许慧敏、耿方丽、杨海波、于小舟

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东明县人民医院检验科,山东菏泽 274500

东明县人民医院普外一科,山东菏泽 274500

临沂市人民医院职业病科,山东临沂 276000

沙门氏菌 腹泻 流行特征 血清型 健康宣教

2024

医学检验与临床
山东省千佛山医院

医学检验与临床

影响因子:0.294
ISSN:1673-5013
年,卷(期):2024.35(11)