ASSOCIATION BETWEEN CEREBRAL MICROBLEEDS AND ENLARGED PERIVASCULAR SPACES
Objective To explore the association between cerebral microbleeds (CMBs) and enlarged perivascular spaces (EPVS) based on magnetic resonance imaging (MRI).Methods We randomly selected 242 patients with cerebrovascular disease who had undergone brain MRI,including T1WI,T2 WI,Flair,DWI,and SWI.The MRI features of CMBs and EPVS (location/size/number) were analyzed to determine their association.Results The incidence of CMBs and EPVS increased with age.Among the 242 patients,164 EPVS lesions were detected in 79 patients,with 90 lesions (54.9%) in the basal ganglia region,47 lesions (28.7%) in the centrum ovale majus,23 lesions (14.0%) in brain lobes,3 lesions (1.8%) in the cerebellar hemisphere,and 1 lesion (0.6%) in the brainstem;1 524 CMBs were detected in 184 patients,with a mean diameter of (2.65±2.81) mm,and there were 112 lesions in deep white and grey matter in the brain,102 lesions in the infratentorial region,and 129 lesions in the cortical or subcortical region.CMBs occurred in 38.5% of patients with EPVS,and there was a positive association between CMBs and EPVS (OR=3.926,95%CI=2.206-10.950,P<0.01).Conclusion There is a positive association between the CMBs and EPVS.
cerebral hemorrhagenervous system diseasesmagnetic resonance imaging