RISK FACTORS FOR SEVERE MEASLES IN CHILDREN AND CLINICAL EFFECT OF TARGETED NURSING
Objective To investigate the risk factors for severe measles in children and the clinical effect of targeted nursing.Methods A retrospective study was performed for the clinical data of 160 children with measles to analyze the risk factors for severe measles in children.A total of 62 children with measles were enrolled in a prospective study and were randomly divided into experimental group and control group.The children in the control group were given routine nursing,and those in the experimental group were given targeted nursing intervention.The clinical outcome was compared between the two groups.Results According to the Logistic regression analysis,reduced CD4 + /CD8 + (odds ratio (OR) =4.669,95 % confidence interval (CI) =1.801-12.104),hypokalemia (OR=4.527,95%CI=1.818-11.273),a recent history of respiratory infection (OR=4.284,95%CI=1.823-10.068),hyponatremia (OR=4.284,95%CI =1.589-8.972),and low hemoglobin (OR =2.561,95%CI=0.165-2.689) were predictive factors for critical conditions.After the implementation of nursing intervention,the experimental group had a significantly higher overall response rate than the control group (93.5% vs 80.6%,x2 =4.026,P<0.05);compared with the control group,the experimental group had significantly shorter fever clearance time,time to disappearance of measles,and length of hospital stay,significantly lower hospital costs,and a significantly lower proportion of children who developed severe measles (t=2.811 4.505,x2=4.276,P<0.05).Conclusion Reduced CD4+/CD8+,hypokalemia,a recent history of respiratory infection,hyponatremia,and low hemoglobin are risk factors for severe measles in children.Early targeted nursing intervention for these risk factors can improve clinical outcome and reduce the incidence of severe measles.