THE VALUE OF STENTING IN THE TREATMENT OF INTERNAL CAROTID ARTERY STENOSIS AFTER RADIOTHERAPY FOR NASOPHARYNGEAL CARCINOMA
Objective To evaluate the value of artery stenting in the treatment of internal carotid stenosis (ICS) after radiotherapy for nasopharyngeal carcinoma (NPC).Methods Eighty patients with cervical stenosis after radiotherapy for NPC treated in our hospital-during January 2010 August 2015-were selected and evenly randomized to observation group and control group.The patients in the observation group were treated with carotid angiography and stenting,and those in the control group were offered drug conservative treatmen.A follow-up of six months was conducted.The success rate of treatment,the results of vascular color Doppler ultrasonography-before and after treatment-as well as recent and mid-term complications bwtenn the two groups were compared.Results The rate of recanalization in the observation group was significantly higher than that in the control group (x2 =48.535,P<0.05).The total proportion of cerebral hemorrhage,vasospasm and thrombus detachment in the observation group was significantly lower than that in the control group (x2 =8.674,P <0.05).During the follow-up period of six months,the proportion of cerebral insufficiency and ischemic stroke in the observation group was significantly lower than that in the control group (x2 =17.202,16.529;P<0.05).After treatment,the diseased-side carotic artery systolic and diastolic blood flow velocity was slower than before treatment (t =9.762,16.971;P <0.05),the blood flow resistance was lower than that before treatment (t =26.000,P<0.05).After treatment,the systolic and diastolic blood flow velocity of the affected-side carotic artery was slower (t =8.677,16.971;P<0.05),and the blood flow resistance was lower than that of the control group (t =24.000,P<0.05).Conclusion Carotid stenting angioplasty for cervical stenosis after radiotherapy for nasopharyngeal carcinoma can effectively open the narrow blood vessels with few treatment-related complications and reliable clinical effectiveness.