ASSOCIATION BETWEEN HYPERTENTION TCM SYNDROME TYPES AND TARGET ORGAN INJURY IN PERIMENOPAUSAL PERIOD OF WOMEN FROM DIFFERENT NATIONALITIES AND REGIONS
Objective To investigate the distribution of traditional Chinese medicine (TCM) syndrome types in patients with perimenopausal hypertension from different nationalities and regions,and the association with target organ injury.Methods Three hundred women with perimenopausal hypertension from different nationalities and regions were enrolled,and their general information,TCM symptoms,and target organ injury information were collected.TCM syndrome types,24 h ambulatory blood pressure,carotid intima-media thickness (IMT),detection rate of carotid plaque,and interventricular septal thickness were compared between the women with perimenopausal hypertension of Uygur and Han nationalities and between the Han patients from Xinjiang and Shanghai.Results In the Uygur group,the TCM syndrome types in patients with perimenopausal hypertension,listed from more common to less common,were as follows:upper hyperactivity of liver Yang,phlegm-dampness stagnation,liverkidney Yin deficiency,deficiency of both Qi and Yin.In the Han group,the TCM syndrome types,listed from more common to less common,were as follows:liver-kidney Yin deficiency,upper hyperactivity of liver Yang,deficiency of both Qi and Yin,and phlegm-dampness stagnation.There was a significant difference in the distribution of TCM syndrome types between the two groups (x 2 =12.61,P ＜0.05).In the Han patients from Xinjiang,the TCM syndrome types,listed from more common to less common,were as follows:upper hyperactivity of liver Yang,liver-kidney Yin deficiency,deficiency of both Qi and Yin,and phlegm-dampness stagnation.In the Han patients from Shanghai,the TCM syndrome types,listed from more common to less common,were as follows:liver-kidney Yin deficiency,upper hyperactivity of liver Yang,deficiency of both Qi and Yin,and phlegm-dampness stagnation.There was no significant difference in the distribution of TCM syndrome types between the two groups (P＞0.05).The patients in Uygur group had significantly higher 24 h systolic pressure and 24 h mean arterial pressure than those in Han group (t =2.85,3.46;P＜0.05).The Han patients from Xinjiang had higher 24 h systolic pressure,24 h diastolic pressure,and 24 h mean arterial pressure than those from Shanghai,but there was no significant difference between them (P ＞ 0.05).The patients with the syndrome of upper hyperactivity of liver Yang had the highest blood pressure in each group.The carotid IMT and detection rate of carotid plaque in the Uygur group were significantly higher than those in Han group (t =4.76,x2 =7.35,P＜0.05).Furthermore,the above two indices in Han patients from Xinjiang were also significantly higher than those in Han patients from Shanghai (t =10.90,x2 =5.26,P ＜0.05).The interventricular septal thickness in the Uygur group was significantly higher than that in the Han group (t =2.52,P＜0.05),and this index in Han patients from Xinjiang was also significantly higher than that in Han patients from Shanghai (t =3.31,P＜0.05).Conclusion Upper hyperactivity of liver Yang is the most commonly seen TCM syndrome type in patients with perimenopausal hypertension of Uygur nationality,and liver-kidney Yin deficiency is the most commonly seen one in patients of Han nationality.The blood pressure is higher in Uygur patients than in Han patients,and is higher in Han patients from Xinjiang than in Han patients from Shanghai.The patients with the syndrome of upper hyperactivity of liver Yang have the highest blood pressure in each group.The Uygur patients have higher IMT,detection rate of carotid plaque,and interventricular septal thickness compared with the Han patients,and the Han patients from Xinjiang also have higher values of the three indices than the Han patients from Shanghai.
hypertensionperimenopauseregionsnationalitiesmedicine, Chinese traditionalorgans at risk
NETL
NSTL
万方数据
维普
