EVALUATION OF LEFT VENTRICULAR GLOBAL MYOCARDIAL STRAIN USING THREE-DIMENSIONAL SPECKLE-TRACKING IMAGING IN PATIENTS WITH CONNECTIVE TISSUE DISEASE
Objective To investigate the clinical value of three-dimensional speckle-tracking imaging (3D-STI) for evaluating the left ventricular global myocardial strain in patients with connective tissue disease (CTD).Methods A total of 30 patients with CTD were selected as the observation group,and 30 healthy volunteers were recruited as the control group.The following parameters were measured by two-dimensional ultrasound:left ventricular end-diastolic volume (LVEDV),left ventricular end-systolic volume (LVESV),stroke volume (SV),and left ventricular ejection fraction (LVEF).The images of apical fourchamber view were analyzed by the TOMTEC software to determine left ventricular global longitudinal strain (GLS),global circumferential strain (GCS) and global radial strain (GRS).All the parameters were compared between the two groups.Results There were no differences in LVEDV,LVESV,SV,and LVEF between the CTD group and the control group (P>0.05).The CTD group showed significantly decreased GLS,GCS,and GRS compared with the control group (t =2.08-3.27,P < 0.05).Conclusion 3D-STI is a reliable tool for evaluation of left ventricular global myocardial strain in patients with CTD and holds promise for clinical application.
echocardiography, three-dimensionalconnective tissue diseasesventricular function, left