首页|SPECT/CT骨断层显像对恶性肿瘤病人腰椎骨盆病变鉴别诊断价值

SPECT/CT骨断层显像对恶性肿瘤病人腰椎骨盆病变鉴别诊断价值

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目的 探讨99 Tcm-亚甲基二膦酸盐(MDP) SPECT/CT骨断层显像对恶性肿瘤病人腰椎骨盆病变鉴别诊断的价值.方法 对135例99Tcm-MDP全身骨显像(WBS)发现腰椎和骨盆放射性异常的恶性肿瘤病人行相应部位SPECT/CT骨断层显像,获得SPECT/CT骨断层显像的资料,由2名有经验的高年资核医学医师共同阅片,对上述资料进行分析,得出最终诊断.计算WES和SPECT/CT骨断层显像能明确诊断为良恶性和不能明确诊断的病灶百分比,并进行比较.结果 135例病人,WBS发现病灶215处,能明确诊断的病灶150处,其中良性病灶130处,肿瘤骨转移病灶20处,占69.77%(150/215);SPECT/CT骨断层显像发现病灶234处,能明确诊断的病灶230处,其中良性病灶180处,肿瘤骨转移病灶50处,占98.29% (230/234).SPECT/CT骨断层显像对恶性肿瘤病人腰椎骨盆病变明确诊断率明显高于WBS,差异有显著意义(x 2=70.09,P<0.05).最终随访结果显示,腰椎和骨盆234处病灶中共182处为良性病变,其中以退行性病变最多见,良性骨肿瘤少见;肿瘤骨转移较少见,占22.22%(52/234).结论 恶性肿瘤病人腰椎骨盆病变SPECT/CT骨断层显像能够比WBS发现更多的病灶,可明显提高诊断的准确性.
VALUE OF SPECT/CT BONE TOMOGRAPHY IN DIFFERENTIAL DIAGNOSIS OF LUMBAR AND PELVIC LESIONS IN PATIENTS WITH MALIGNANT TUMOR
Objective To investigate the value of 99Tcm-MDP SPECT/CT bone tomography in the differential diagnosis of lumbar and pelvic lesions in patients with malignant tumor.Methods SPECT/CT bone tomography was performed for 135 patients with malignant tumor who had radioactive anomalies in the lumbar vertebra and the pelvis on 99Tcm-MDP whole-body scan (WBS),and the data of SPECT/CT bone tomography were obtained.Two experienced senior nuclear medicine physicians read the radiographs together.These data were analyzed to give a final diagnosis.The proportion of benign or malignant lesions or lesions without a definite diagnosis evaluated by WBS or SPECT/CT bone tomography was calculated and compared.Results For all 135 patients,215 lesions were found by WBS,among which 150 (69.77%) had a definite diagnosis,including 130 benign lesions and 20 bone metastatic lesions.A total of 234 lesions were found by SPECT/CT bone tomography,among which 230 (98.29%)had a definite diagnosis,including 180 benign lesions and 50 bone metastatic lesions.SPECT/CT bone tomography had a significantly higher diagnostic rate of lumbar and pelvic lesions than WBS (x2 =70.09,P<0.05).Follow-up results showed that of all 234 lumbar and pelvic lesions,182 were benign lesions,most of which were degenerative lesions,and benign bone tumor was rare.Of all 234 lesions,52 (22.22%) were bone metastatic lesions of tumor.Conclusion In patients with malignant tumor,SPECT/CT bone tomography can find more lumbar and pelvic lesions than WBS,which significantly improves diagnostic accuracy.

bone neoplasmsspinal diseasesneoplasm metastasistomography, emission-computed, single-photon

赵莉、袁明刚、孔宁宁、李杰、于华

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青岛市中心医院核医学科,山东青岛266042

骨肿瘤 脊柱疾病 肿瘤转移 体层摄影术,发射型计算机,单光子

青岛市医药科研指导计划资助项目

2015WJZD-051

2017

齐鲁医学杂志
青岛大学医学院

齐鲁医学杂志

影响因子:0.609
ISSN:1008-0341
年,卷(期):2017.32(4)
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