CLINICAL VALUE OF SERUM TUMOR MARKERS IN DIAGNOSIS OF EARLY-STAGE SMALL CELL LUNG CANCER
Objective To investigate the clinical value of serum tumor markers in the diagnosis of early-stage small cell lung cancer.Methods A total of 60 patients with early-stage small cell lung cancer who were treated in our hospital from January 2014 to December 2015 were enrolled as observation group,and another 60 patients with solid lung lesions who were hospitalized during the same period of time were enrolled as control group.Tumor markers were measured for all patients,and the positive rates of triple and quadruple measurement of tumor markers were compared.Results The observation group had significantly higher serum levels of carcinoembryonic antigen (CEA),cytokeratin 21 1 (CYFRA21 1),neuron-specific enolase (NSE),and carbohydrate antigen 125 (CA125) than the control group (t =19.985-46.924,P＜0.01).The triple and quadruple measurement of tumor markers such as CEA,CYFRA21-1,NSE,and CA125 in small cell lung cancer patients showed that the positive rate of quadruple measurement reached 85.71％.Conclusion Serum tumor markers play an important role in the diagnosis of early stage small cell lung cancer,and the combined measurement of various tumor markers can significantly improve the early detection rate of small cell lung cancer.
NETL
NSTL
万方数据
维普
